Associate Director, Clinical Pharmacology (Remote)

Travere Therapeutics; Kansas City (MO); Hybrid; USD 150,000 - 195,000; Full time

Job summary

Travere Therapeutics is seeking an Associate Director of Clinical Pharmacology in San Diego with a strong PK/PD and translational pharmacology focus. You will lead strategy across programs, integrating PK/PD and DDIs, and collaborate with regulatory teams to inform submissions and paths to approval.

The role requires a Ph.D. or PharmD with extensive leadership in clinical pharmacology, and a willingness to travel up to 10% domestically and internationally.

Qualifications

• Ph.D. degree or equivalent required; equivalent education/experience considered.
• 4+ years of experience required or PharmD with 8+ years in a relevant field.
• Experience across multiple therapeutic and/or functional areas.
• Experience across development phases.
• Demonstrated PK/PD, Biopharmaceutics, and Pharmacometric leadership across multiple projects.
• Clinical pharmacology input for regulatory submissions and protocols.

Responsibilities

• Lead the development and execution of clinical pharmacology strategy for assigned development programs, integrating pharmacokinetics (PK), pharmacodynamics (PD), and drug-drug interaction assessments into all stages of clinical trials.
• Represent independently Clinical Pharmacology and provide clinical pharmacology support and guidance to clinical stage project teams.
• Develop and oversee the design and implementation of clinical pharmacology studies (e.g., dose escalation, PK/PD modeling) for early drug candidates, ensuring optimal dosing strategies and evidence generation.
• Provide clinical pharmacology input for regulatory submissions such as briefing documents, IND, CTA and NDA.
• Reviews clinical protocols and scientific reports for regulatory filings and anticipates regulatory questions.
• Prepare and input independently appropriate documents or sections of clinical protocols, Investigator Brochures, Clinical Study Reports with respect to Clinical Pharmacology studies or data.
• Closely partner with Research, Bioanalytical, Clinical, Regulatory, Project Management, and other R&D functions.
• This position will play a key role in delivering strategic and well-timed clinical pharmacology input at key decision points along the development path.

Skills

Leadership

PK/PD

Biopharmaceutics

Pharmacometrics

Project management

Scientific leadership

Communication

Education

Ph.D. or PharmD

8+ years experience

Job description

Travere Therapeutics is seeking an Associate Director of Clinical Pharmacology in San Diego with a strong PK/PD and translational pharmacology focus. You will lead strategy across programs, integrating PK/PD and DDIs, and collaborate with regulatory teams to inform submissions and paths to approval.

The role requires a Ph.D. or PharmD with extensive leadership in clinical pharmacology, and a willingness to travel up to 10% domestically and internationally.