Applied Scientist, Life Sciences AI for Clinical Trials

Amazon Science; Seattle (WA); On-site; USD 143,000 - 193,000; Full time

Job summary

Amazon Science is seeking an Applied Scientist to build models and methods behind our life sciences AI products, with a primary focus on clinical trial operations and agentic reasoning. You will design, train, and evaluate systems that reason over complex clinical and operational logic, and ship them into products customers use directly.

You will work closely with senior and principal scientists on well-scoped research problems, own your results end to end, and see your work reach production.

Qualifications

• Master's degree or above in a relevant field.
• Experience with LLMs, reasoning systems, and agentic AI, including architecture design, training, fine-tuning, and evaluation.
• Experience building or evaluating agentic systems (planning, tool use, retrieval, verification).
• Publication record at ML or computational biology venues.
• PhD in Machine Learning, Computer Science, Computational Biology, or related field, or MS with equivalent applied research experience.

Responsibilities

• Design, train, fine-tune, and evaluate LLM-based agentic systems that reason over clinical protocols, regulatory standards, and operational workflows.
• Build rigorous evaluation harnesses and benchmarks to measure agent reliability, faithfulness, and failure modes in high-stakes domains.
• Develop model customization methods (fine-tuning, RLHF, retrieval augmentation, domain adaptation) that help customers get better outputs on their own data with less effort.
• Contribute to graph-based and causal modeling approaches for clinical trial operations.
• Partner with Life Sciences domain experts, product, and engineering to translate scientific challenges into shipped capabilities.
• Own experiments end to end: problem framing, implementation, evaluation, iteration, and hand-off to production.
• Publish at top-tier venues where the work supports it.
• Contribute to drug discovery efforts (protein engineering, antibody design) as opportunities arise.

Skills

LLMs

Agentic AI

Research

Education

Master's degree or above in a relevant field

Tools

Python

PyTorch

JAX

Job description

Amazon Science is seeking an Applied Scientist to build models and methods behind our life sciences AI products, with a primary focus on clinical trial operations and agentic reasoning. You will design, train, and evaluate systems that reason over complex clinical and operational logic, and ship them into products customers use directly.

You will work closely with senior and principal scientists on well-scoped research problems, own your results end to end, and see your work reach production.