Lead Applied Scientist, Life Sciences AI & LLMs

Amazon Science; Seattle (WA); On-site; USD 199,000 - 269,000; Full time

Job summary

Amazon Science in Seattle is seeking a Principal Applied Scientist to set the scientific direction for our life sciences AI portfolio. You will define research agendas, architect novel approaches, and deliver models that empower customers with capabilities not previously available.

You will work across drug discovery and clinical trial operations, owning end-to-end scientific solutions from research through production, mentoring applied scientists, and publishing at top venues.

Qualifications

• PhD in ML, CS, computational biology, or related field.
• Experience as a senior or principal applied scientist solving complex problems.
• Deep expertise in LLMs, reasoning systems, and agentic AI.
• Strong publication record in top ML or computational biology venues.
• Experience translating research into products and 0-to-1 AI services.

Responsibilities

• Set scientific vision and research agenda for LLM reasoning, agentic AI, and biological model customization across the portfolio.
• Innovate on LLM reasoning, planning, and agentic approaches for complex scientific and regulatory workflows.
• Develop model customization methods (fine-tuning, RLHF, retrieval augmentation, domain adaptation).
• Advance methods to adapt and extend biological foundation models for customer-specific therapeutic applications.
• Publish at top venues and mentor applied scientists across the team.

Skills

LLM reasoning

Agentic AI

Python

PyTorch

JAX

Model customization

Publications

Education

PhD in ML/CS/Computational Biology

Tools

PyTorch

JAX

Job description

Amazon Science in Seattle is seeking a Principal Applied Scientist to set the scientific direction for our life sciences AI portfolio. You will define research agendas, architect novel approaches, and deliver models that empower customers with capabilities not previously available.

You will work across drug discovery and clinical trial operations, owning end-to-end scientific solutions from research through production, mentoring applied scientists, and publishing at top venues.