Applied AI Lead Scientist – Cell & Gene Therapy

Johnson Johnson; Malvern (Chester County); On-site; USD 180,000 - 260,000; Full time

Job summary

Johnson & Johnson in Malvern, PA seeks a Senior Scientist, AI Lead to drive AI initiatives across Cell & Gene Therapy. You will lead cross-functional teams, translate scientific needs into AI use cases, and shape innovative AI solutions that integrate with scientific workflows and digital labs.

You will partner with research and manufacturing teams to ensure responsible AI practices, scalability, and measurable impact on development timelines in a fast-paced pharma environment.

Qualifications

• Strong scientific background in chemical engineering, biochemistry or related fields.
• Experience applying AI to pharmaceutical development and R&D.
• Ability to translate scientific needs into AI use cases.

Responsibilities

• Lead cross-functional AI projects supporting Cell & Gene Therapy development priorities. Define project scope, plans, resources, milestones, decision points, and measurable success criteria.
• Coordinate cross-functional teams and external partners; manage risks, dependencies, decisions, and stakeholder communication.
• Lead the design, prototype, test, and iteration of AI solutions across machine learning, generative and agentic AI, natural language processing, computer vision, knowledge graphs, predictive analytics, and AI-enabled digital twins.
• Evaluate solutions for model performance, scientific validity, usability, reliability, and business value.
• Integrate successful solutions into scientific workflows, data platforms, digital twins, and automated laboratory environments with reuse and scale in mind.
• Embed responsible AI and lifecycle practices, including fit-for-purpose validation, transparency, privacy, security, governance, human oversight, performance monitoring, and clear communication of model limitations.
• Partner with process development, analytical, manufacturing, and business teams to identify scientific and operational challenges that could benefit from AI.
• Translate domain needs into clear AI use cases, user requirements, data needs, and expected outcomes.
• Assess use cases based on scientific value, business impact, data readiness, technical feasibility, risk, and scalability.
• Serve as a key interface between scientific subject matter experts, data science, and technology teams.
• Establish productive relationships with internal data science teams, technology partners, academic collaborators, and vendors.
• Bring external developments and best practices into the organization while avoiding fragmented or duplicative solution

Skills

AI Leadership

Cross-functional collaboration

Project management

Machine Learning

Deep Learning

NLP

Computer Vision

Generative models

Knowledge graphs

Digital twins

Responsible AI

Job description

Johnson & Johnson in Malvern, PA seeks a Senior Scientist, AI Lead to drive AI initiatives across Cell & Gene Therapy. You will lead cross-functional teams, translate scientific needs into AI use cases, and shape innovative AI solutions that integrate with scientific workflows and digital labs.

You will partner with research and manufacturing teams to ensure responsible AI practices, scalability, and measurable impact on development timelines in a fast-paced pharma environment.