Analytical Methods Scientist—Instrumentation & Training

Go Huskies

Seattle (WA)

Hybrid

USD 90,000 - 108,000

Full time

14 days+

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Job summary

The Institute for Protein Design (IPD) at the University of Washington is seeking an Analytical Methods and Instrumentation Scientist (RS3) to strengthen analytical and purification capabilities. You will develop general-use methods for small-molecule analysis, enzyme characterization, and chromatography workflows, and train researchers across core instrumentation such as FPLC, HPLC, LC‑MS, and SPR.

This role emphasizes method development, data analysis, SOP creation, and providing guidance to

Qualifications

  • Bachelor's degree in Biochemistry, Biology, Physics or related field with four years of experience in small-molecule analytical techniques.
  • Hands-on experience with small-molecule analytical techniques including method development, optimization, and validation.
  • Proficiency with U/HPLC (Agilent) systems, routine maintenance and advanced method setup.
  • Experience operating LC-MS (Agilent) instruments including data acquisition, analysis and interpretation.
  • Strong understanding of chromatography principles and purification using FPLC (ÄKTA).
  • Familiarity with SPR (Cytiva) instrumentation and workflows.
  • Experience mentoring and training trainees in analytical techniques and instrumentation use.

Responsibilities

  • Mentor and train graduate students, postdocs, and staff in analytical techniques such as FPLC, U/HPLC, LC-MS and SPR.
  • Develop, validate, and maintain general-use analytical and purification methods for small molecules and enzymes; create SOPs and reference datasets.
  • Oversee instrumentation maintenance, ensure high throughput readiness, monitor performance, and coordinate service as needed.

Skills

Mentoring
Analytical problem-solving
Scientific communication

Education

Bachelor's degree in Biochemistry/ Biology/ Physics or related field
Doctorate degree in chemistry/ biochemistry/ chemical engineering or related field

Tools

FPLC (AKTA)
U/HPLC (Agilent)
LC-MS (Agilent)
SPR (Cytiva)

Job description

The Institute for Protein Design (IPD) at the University of Washington is seeking an Analytical Methods and Instrumentation Scientist (RS3) to strengthen analytical and purification capabilities. You will develop general-use methods for small-molecule analysis, enzyme characterization, and chromatography workflows, and train researchers across core instrumentation such as FPLC, HPLC, LC‑MS, and SPR.

This role emphasizes method development, data analysis, SOP creation, and providing guidance to

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