Analytical Chemistry Research Advisor - Synthetic Molecule Design and Development (SMDD)

Eli Lilly and Company; Indianapolis (IN); On-site; USD 80,000 - 110,000; Full time

Job summary

An established industry player is seeking an Analytical Chemistry Research Advisor to join their innovative team in Indianapolis. This role is pivotal in developing analytical methodologies for characterizing oligonucleotides, peptides, and small molecules, contributing to the advancement of life-changing medicines. You will engage with a diverse team of scientists and engineers, utilizing your expertise in analytical techniques such as mass spectrometry and chromatography to drive impactful projects. If you are passionate about scientific discovery and thrive in a dynamic environment, this opportunity offers a chance to make a real difference in healthcare and contribute to groundbreaking research.

Qualifications

• PhD in Analytical Chemistry or related field is required.
• Experience with multiple analytical techniques is essential.

Responsibilities

• Develop analytical methodologies for oligonucleotides and small molecules.
• Collaborate with partners to establish robust control strategies.
• Engage with scientists to improve scientific processes.

Skills

Analytical Techniques

UHPLC

Mass Spectrometry

IR Spectroscopy

Raman Spectroscopy

UV Spectroscopy

NMR

Data Interpretation

Problem-Solving Skills

Communication Skills

Education

PhD in Analytical Chemistry

PhD in Biochemistry

PhD in Chemistry

Tools

Chromatography

Mass Spectrometry

Chemometrics

Job description

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

The Synthetic Molecule Design and Development (SMDD) organization is responsible for the development of synthetic drug substances and drug products from the pre-clinical phase through commercialization. Our scientists and engineers develop innovative technical solutions to advance an exciting portfolio that includes small molecules, peptides, oligonucleotides, and other emerging therapeutic modalities. By encouraging a hardworking, culturally diverse workforce that exhibits deep technical expertise, SMDD delivers on these responsibilities and helps bring the next generation of life-changing medicines to patients!

SMDD has an exciting opportunity for an Analytical Chemistry Research Advisor to join our multidisciplinary team of chemists, engineers, and formulation scientists. Empowered by access to world-class capabilities and extensive pharmaceutical development experience, you will help deliver technical solutions that enable deeper understanding of processes and products across the portfolio. Ideal candidates will possess experience across multiple analytical techniques (e.g., UHPLC, mass spectrometry, IR, Raman, UV, NMR), demonstrate an aptitude in technical problem-solving, and be motivated to work both independently and collaboratively in a dynamic environment.

Position Responsibilities:

• Enable the design, development, and implementation of analytical methodologies for the characterization and analysis of oligonucleotides, peptides, and small molecules.
• Contribute to the establishment of robust control strategies through generation of data, development of analytical methods, and collaboration with internal and external development partners.
• Demonstrate proficiency in multiple modes of chromatography, mass spectrometry, optical spectroscopy, instrument engineering, or other analytical technologies.
• Develop strategies for instrument integration with automated data analysis workflows and process sampling interfaces.
• Engage with scientists across development and manufacturing to develop a deep understanding of new initiatives and improve existing scientific processes.
• Identify ground-breaking analytical technologies as well as trends in analytical chemistry, synthetic chemistry, and chemical engineering.
• Identify and exploit new scientific concepts, strong problem-solving skills, and be self-motivated to contribute across multiple projects.
• Demonstrate strong written and verbal communication skills to speak to both technical and business-related implications of your work.

Basic Qualifications:

• PhD in Analytical Chemistry, Biochemistry, Chemistry, or related field.

Additional Skills/Preferences:

• Reversed phase chromatography, ion exchange chromatography, size exclusion chromatography, chiral chromatography, gas chromatography.
• Hands-on experience with mass spectrometry in the characterization and quantitation of synthetic molecules including oligonucleotides, peptides, and small molecules.
• Experience with data interpretation, including the application of chemometrics, multivariate modeling, and other data manipulation tools.
• Learning agility and demonstrated ability to apply technical knowledge to improve the understanding of chemical systems or improve analytical techniques.
• Ability to balance multiple activities, prioritize evolving project needs, and handle ambiguity.

Additional Information:

• Possible exposure to chemicals, allergens, and loud noises.
• Occasional travel (0 to 10%).
• Position Location: Indianapolis, IN; Lilly Technology Center-North (LTC-N).