Materials Science Development Scientist-SMDD

Initial Therapeutics, Inc.; Indianapolis (IN); On-site; USD 63,000 - 163,000; Full time

Job summary

An established industry player is seeking a materials scientist to join a dynamic team in Indianapolis. This role focuses on solid-state characterization and crystallization of innovative drug substances, contributing to the development of life-changing medicines. Ideal candidates will leverage their technical expertise and problem-solving skills to advance pharmaceutical development. With access to world-class capabilities, you'll collaborate with a multidisciplinary team to tackle complex challenges and drive impactful results. This position offers a unique opportunity to make a significant difference in the healthcare landscape while enjoying a comprehensive benefits package.

Benefits

Company bonus

401(k) plan

Medical benefits

Dental benefits

Vision benefits

Vacation benefits

Life insurance

Employee assistance program

Fitness benefits

Employee clubs and activities

Qualifications

• Experience in solid-state characterization and form selection.
• Familiarity with solid-state analytical tools and crystallization instrumentation.

Responsibilities

• Conduct solid-form screening and characterization of drug substances.
• Partner with development groups to solve complex technical problems.
• Document scientific results and maintain laboratory instrumentation.

Skills

Solid-state characterization

Problem-solving skills

Written and verbal communication

Learning agility

Education

BS degree in a physical science

Tools

XRPD

DSC

TGA

DVS

HPLC

Easymax

Crystal 16

Job description

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $63,000 - $162,800.

Organization Overview:

The Synthetic Molecule Design and Development (SMDD) organization is responsible for the development of synthetic drug substances and drug products from the pre-clinical phase through commercialization. Our scientists and engineers develop innovative technical solutions to advance an exciting portfolio that includes small molecules, peptides, oligonucleotides, and other emerging therapeutic modalities. By encouraging a hardworking, culturally diverse workforce that exhibits deep technical expertise, SMDD delivers on these responsibilities and helps bring the next generation of life-changing medicines to patients!

SMDD has an exciting opportunity for a materials scientist to join our multidisciplinary team of chemists, engineers, and formulation scientists. Empowered by access to world-class capabilities and extensive pharmaceutical development experience, you will help deliver technical solutions that enable deeper understanding of processes and products across the portfolio. Ideal candidates will possess experience in solid-state characterization and form selection in support of pre-clinical studies, clinical studies, drug manufacturing, and drug product design for novel small molecules and peptides.

Responsibilities:

• Solid-form screening and characterization of novel small molecules, peptides, oligonucleotides, and intermediates.
• Scale up crystallization of small molecules and peptide fragments.
• Partner with development groups to solve complex technical problems.
• Leverage learning agility and problem-solving skills in applying solid-state principles to the delivery of new therapeutic modalities.
• Engage in development of workflows for solid-state integration with automated data analysis.
• Documentation of scientific results.
• Maintain laboratory area and instrumentation related to solid state and process crystallization.
• Demonstrate strong written and verbal communication skills.

Basic Requirements:

• BS degree in a physical science (e.g. chemistry), pharmaceutics, or related discipline.

Additional Skills/Preferences:

• Familiarity with standard solid-state analytical tools (e.g. XRPD, DSC, TGA, DVS, HPLC) and optionally crystallization instrumentation (e.g. Easymax, Crystal 16).
• Understanding of solid form screening including salt and cocrystal screening for pharmaceutical solids.
• Experience with scale-up crystallization of small molecules or peptides.
• Ability to balance multiple activities, prioritize evolving project needs, and handle ambiguity.
• Understanding of pharmaceutical solid-state science and its impact on drug product performance and manufacturing.

Additional Information:

• Possible exposure to chemicals, allergens, and loud noises.
• Occasional travel (0 to 10%).
• Position Location: Indianapolis, IN; Lilly Technology Center-North.

Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form (https://careers.lilly.com/us/en/workplace-accommodation) for further assistance.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).

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