AI-Driven Therapeutics Architect

Breakout Ventures; San Francisco (CA); Hybrid; USD 150,000 - 210,000; Full time

Benefits offered by this job

Competitive compensation

Comprehensive healthcare

Unlimited time off

Parental leave

Hybrid/remote-friendly

Job summary

NOETIK is an AI-native biotech focused on discovering and developing precision cancer therapies. We combine self-supervised machine learning and multimodal data generated in-house to identify targets and advance drugs from discovery to clinical development.

Headquartered in South San Francisco, CA with a hybrid, remote-friendly culture, we value flexibility, collaboration across biology, AI, engineering, and therapeutics, and strong scientific judgment.

Qualifications

• PhD, MD, or equivalent experience in cancer biology, immunology, pharmacology, molecular biology, translational medicine, or a related discipline.
• Experience on drug discovery or development programs with go/no-go decision experience.
• Ability to translate hypotheses into viable therapeutic programs across discovery to translational stages.
• Comfort mixing biology with machine learning, computational science, and strategy.
• Hands-on use of modern AI tools in scientific work with measurable impact on decisions.
• Systems-thinking mindset with the ability to prioritize across multiple opportunities.
• Excellent scientific judgment and strong communication across stakeholders.
• Bonus: experience with computational biology, data science, ML, or programming (Python, R, SQL).

Responsibilities

• Own the evaluation and championing of biological insights and therapeutic opportunities from first look through portfolio nomination.
• Work cross-functionally to drive programs forward by defining questions, decision criteria, and actions at each stage.
• Develop platform-informed hypotheses around targets, mechanisms, patient populations, biomarkers, and clinical strategy.
• Build evidence packages that inform investment, partnering, and development decisions.
• Design and improve AI-enabled scientific workflows that increase the durability and quality of therapeutic decision-making.
• Prioritize across the portfolio by balancing biological opportunity, feasibility, clinical impact, and strategic fit.

Skills

Cancer biology

Immunology

Pharmacology

Molecular biology

Translational medicine

Machine learning

Data science

Python

R

SQL

Strategic thinking

Education

PhD, MD, or equivalent experience in cancer biology or related discipline

Tools

Python

R

SQL

Job description

NOETIK is an AI-native biotech focused on discovering and developing precision cancer therapies. We combine self-supervised machine learning and multimodal data generated in-house to identify targets and advance drugs from discovery to clinical development.

Headquartered in South San Francisco, CA with a hybrid, remote-friendly culture, we value flexibility, collaboration across biology, AI, engineering, and therapeutics, and strong scientific judgment.