Senior Scientist, Spatial Biology & AI for Oncology

Breakout Ventures; South San Francisco (CA); Vor Ort; USD 150.000 - 230.000; Vollzeit

Benefits dieser Stelle

Health insurance

401(k) with employer match

Stock options

Parental leave

Zusammenfassung

NOETIK is seeking a Senior Scientist to drive hands-on spatial biology experiments on human tissue samples, with a focus on in situ hybridization and proteomics, while contributing to AI model training data. The role emphasizes rigorous data quality, protocol development, and cross-functional collaboration with Histology and ML teams.

The ideal candidate will mentor junior staff, troubleshoot complex assays, and maintain comprehensive documentation to support scalable data pipelines for

Qualifikationen

• PhD in molecular biology, genomics, cell biology, biomedical engineering, or related field.
• 2-5+ years of industry hands-on experience with spatial transcriptomics (CosMx, Xenium, MERFISH…); CosMx preferred.
• Experience with spatial proteomics platforms and immunofluorescence panel design is desirable.
• Ability to troubleshoot wet-lab and imaging-based assay failures and identify root causes.
• Strong knowledge of QC metrics for spatial transcriptomics and handling batch effects.

Aufgaben

• Independently plan, perform and troubleshoot spatial biology experiments on human tissue samples.
• Establish and enforce data quality standards across experiments and analysis pipelines.
• Mentor and train team members on technique, rigor, and quality judgment.
• Collaborate with Histology and Scientific Operations to ensure seamless project execution.
• Lead cross-functional projects with Engineering and ML teams to design data for AI model training.
• Participate in lab meetings and foster a collaborative, innovation-driven culture.

Kenntnisse

Spatial transcriptomics

In situ hybridization

Proteomics

Data QC metrics

Leadership

Troubleshooting

Computational fluency

Documentation

Ausbildung

PhD in molecular biology/genomics

Tools

CosMx

Xenium

MERFISH

Akoya PhenoCycler

Lunaphore

Python/R

Jobbeschreibung

NOETIK is seeking a Senior Scientist to drive hands-on spatial biology experiments on human tissue samples, with a focus on in situ hybridization and proteomics, while contributing to AI model training data. The role emphasizes rigorous data quality, protocol development, and cross-functional collaboration with Histology and ML teams.

The ideal candidate will mentor junior staff, troubleshoot complex assays, and maintain comprehensive documentation to support scalable data pipelines for