AI-Driven High-Throughput Biology Scientist

Vertex Pharmaceuticals Inc (US); Boston (MA); On-site; USD 106,000 - 158,000; Full time

Benefits offered by this job

Annual bonus

Equity awards

Paid time off

Commuting subsidy

Educational assistance

Job summary

Vertex is seeking a Research Scientist to develop and implement high-throughput human biology assays, integrating automation and AI-enabled tools to accelerate discovery programs. The role involves cross-disciplinary collaboration, translating scientific needs into robust workflows, and ensuring data-driven decision making.

The candidate will contribute from concept to implementation, applying expertise in cellular and molecular biology, lab automation, and data analysis in a fast-paced, on-site

Qualifications

• PhD in a relevant scientific discipline with 0-3 years of relevant experience.
• Scientifically curious, driven and independent, motivated by making impact to project progression.
• Demonstrated creativity in biological assay development.
• Foundational molecular biology and cell biology laboratory experience in multi-well plate formats, including complex human cellular assays, immunoassays, qPCR, high-content imaging, and other relevant functional and target engagement assays

Responsibilities

• Develop, optimize, and implement high-throughput human biology assays to address key questions or challenges in discovery biology across multiple programs
• Build integrated automation workflows for cellular and biochemical assays leveraging robotics, high-throughput liquid handling, and custom computational solutions
• Execute screening and follow-up studies, analyze complex datasets, and translate findings into actionable recommendations for project teams
• Troubleshoot assay and automation performance and drive continuous improvements in throughput, data quality, and operational reliability
• Identify unmet scientific needs relevant to our research areas and develop solutions from conceptualization through prototyping and implementation
• Evaluate emerging technologies and apply promising solutions to internal programs
• Represent the High Throughput Human Biology group as part of highly collaborative, interdisciplinary teams, communicate results clearly and maintain rigorous, reproducible records

Skills

Python

R

MATLAB

Collaborative teamwork

Education

PhD in relevant scientific discipline

Tools

Laboratory automation

Job description

Vertex is seeking a Research Scientist to develop and implement high-throughput human biology assays, integrating automation and AI-enabled tools to accelerate discovery programs. The role involves cross-disciplinary collaboration, translating scientific needs into robust workflows, and ensuring data-driven decision making.

The candidate will contribute from concept to implementation, applying expertise in cellular and molecular biology, lab automation, and data analysis in a fast-paced, on-site