Accounting Manager

Egenesisbio; Cambridge (MA); On-site; USD 120,000 - 154,000; Full time

Job summary

eGenesis, Inc is seeking a highly motivated Accounting Manager to lead the day-to-day close process in Cambridge, MA. Reporting to the Controller, you will own the end-to-end close, manage general ledger, payables, accruals, and ensure US GAAP compliance as a public company.

The ideal candidate has 5+ years in accounting, public company close experience, Netsuite proficiency, biotech industry familiarity, and a track record building scalable controls and processes in a fast-paced environment.

Qualifications

• Bachelor’s degree in Accounting or Finance required.
• Public company close experience required.
• Biotech or life sciences industry experience preferred.
• CPA preferred.
• Strong analytical, organizational, and communication skills.

Responsibilities

• Own end-to-end financial close process (GL, AP, accruals).
• Deliver accurate monthly, quarterly, and annual statements per US GAAP.
• Estimate accruals for R&D and CRO arrangements.
• Support ICFR design and SOX readiness.
• Maintain financial statements and schedules; ensure audit readiness.
• Manage NetSuite as system of record; partner with FP&A.
• Lead a high-performance accounting team.

Skills

GAAP knowledge

Public company close

Analytical skills

Independent work

Education

Bachelor’s degree in Accounting or Finance

CPA preferred

Tools

NetSuite

Job description

About eGenesis

eGenesis is a clinical-stage biotechnology company developing human-compatible engineered organs to address the severe global organ shortage. The Company’s proprietary genome engineering platform enables extensive, multiplex gene edits to remove key biological barriers, add protective human transgenes, and inactivate endogenous retroviruses. EGEN-2784, a genetically engineered porcine kidney, is the Company’s lead program and is currently being evaluated in a multi-patient Expanded Access study at MGH. eGenesis is headquartered in Cambridge, MA.

POSITION SUMMARY

eGenesis, Inc is seeking a highly motivated Accounting Manager to execute the day-to-day functions during a pivotal period of growth. Reporting to the Controller, this role will be responsible for all aspects of the monthly and quarterly close process. This highly visible role will use strong organizational skills and attention to detail to identify and implement operational decisions with accounting implications. The ideal candidate combines strong technical GAAP knowledge with hands‑on execution, thrives in a fast‑paced and evolving environment, and is energized by building scalable processes from the ground up. This is a full‑time role based in Cambridge, MA.

• Own the end-to‑end financial close process, including general ledger, accounts payables, and accruals, delivering accurate and timely monthly, quarterly, and annual financial statements in compliance with U.S. GAAP
• Account for R&D expenses, clinical trial accruals and prepaids, and CRO vendor arrangements, coordinating closely with clinical and operations teams to estimate accruals
• Help design, implement, and maintain internal controls over financial reporting (ICFR) in preparation for SOX compliance and public‑company requirements
• Support preparation and maintenance of financial statements and supporting schedules, ensuring disclosures are accurate, complete, and audit‑ready
• Manager Senior Accountant, fostering a high‑performance team environment
• Design, implement, and maintain a robust internal control environment appropriate for a company operating under public company accounting standards
• Manage NetSuite as the system of record, partnering with FP&A on chart of accounts governance, reporting configuration, and process improvements

• Bachelor’s degree in Accounting or Finance required; CPA preferred
• 5+ years of progressive accounting experience, including public accounting and/or industry experience
• Public company accounting experience preferred, including demonstrated ownership of monthly close process under public company reporting timelines
• Biotech or life sciences industry experience required; familiarity with clinical‑stage accounting (CRO accrual methodology, collaboration agreement) strongly preferred
• Hands‑on proficiency with NetSuite required
• Excellent analytical, organizational, and communication skills, with strong attention to detail
• Ability to work independently, prioritize, and adapt in a fast‑changing environment

Base pay range for this job is $120,000 - $154,000.