Sr Research Asst

NHG Health; Singapore; On-site; SGD 60,000 - 75,000; Full time

Job summary

NHG Health Infectious Disease Research Laboratory seeks a Senior Research Assistant to advance bacteriology-focused projects in a dynamic team environment. The role emphasizes rigorous laboratory work, data management and collaborative study execution.

The successful candidate will design, perform and analyze experiments, process clinical samples, and contribute to publications while mentoring junior staff and ensuring compliance with SOPs and safety regulations.

Qualifications

• Bachelor’s or Master’s degree in Microbiology, Bacteriology, or related field.
• 3–5 years of laboratory experience in bacteriology or clinical microbiology.
• Proficiency in bacteriology techniques including culture, identification, AST, and broth dilution.
• Experience with MALDI-TOF mass spectrometry is preferred.
• Familiarity with WGS methodologies and bioinformatics analysis tools.

Responsibilities

• Design, execute and analyze research related to Bacteriology.
• Prepare, handle and process clinical samples.
• Perform antimicrobial susceptibility testing and broth dilution; interpret MIC.
• Design and perform molecular assays (DNA/RNA extraction, PCR/qPCR, gel electrophoresis, WGS).
• Assist in data analysis, reports and publications.
• Maintain SOPs and risk assessments for the department.
• Plan study logistics and liaise with internal and external parties.

Skills

Bacteriology

Lab techniques

Data analysis

Communication

Teamwork

Office suite

Education

Bachelor’s or Master’s in Microbiology or related field

Tools

MALDI-TOF MS

Whole Genome Sequencing

Bioinformatics tools

Job description

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We are seeking a motivated and skilled Senior Research Assistant to join our team at the Infectious Disease Research Laboratory. The ideal candidate will have a strong background in bacteriology, excellent laboratory skills, and the ability to work independently and collaboratively on various research projects. This is an excellent opportunity for a detail-oriented individual to contribute to impactful research in infectious diseases.

MAIN DUTIES AND RESPONSIBILITIES

• Assist in the design, execution and analysis of research related to Bacteriology.
• Preparation, handling and processing of clinical samples.
• Advanced microbial techniques such as bacterial culture techniques (aerobic and anaerobic), isolation and identification of bacterial strains by colony morphology and MALDI-TOF mass spectrometry, and use of selective and differential media.
• Antimicrobial Susceptibility Testing (AST) – Performing standard methods such as disk diffusion, broth microdilution, and E-test. Analyzing and interpreting antibiotic susceptibility profiles.
• Broth Dilution Techniques – Preparation and dilution of antibiotic solutions. Evaluating minimum inhibitory concentrations (MIC).
• Design and perform molecular assays, including DNA/RNA extraction, PCR/qPCR, gel electrophoresis and Whole Genome Sequencing (WGS).
• Assist in data analysis and management, preparing reports, and publications.
• Assist in the development, implementation and revision of standard operating procedure(s) and risk assessments for department.
• Assist in planning of study logistics, workflow, documentation and execution of new studies, liaising with internal and external parties as needed.
• Work closely with researchers and other team members to support ongoing projects.
• Train and mentor junior research assistants and interns in laboratory techniques and safety practices.
• Assist in general laboratory maintenance and perform other duties as directed by supervisors and HOD, including work areas not mentioned here.

JOB REQUIREMENTS

• Bachelor’s or Master’s degree in Microbiology, Bacteriology, or a related field.
• Minimum of 3-5 years of laboratory experience in bacteriology or microbiology clinical research.
• Proficiency in bacteriology laboratory techniques, including culture, identification, AST, and broth dilution.
• Experienced in working with common hospital bacteria such as MRSA, C. diff, E.coli, Pseudomonas aeruginosa, Klebsiella species, Enterococcus species and Acinetobacter baumannii.
• Hands-on experience with MALDI-TOF mass spectrometry is preferred.
• Familiarity with whole genome sequencing methodologies and bioinformatics analysis tools.
• Strong analytical skills and attention to detail.
• Good organizational skills and able to handle multiple tasks simultaneously.
• Proficient in Microsoft Office Suite (Word, Excel, PowerPoint).
• Excellent communication and interpersonal skills.
• Ability to work independently and as part of a team.