Research Fellow / Research Engineer (Biosensor and microbial detection) - JP2

Singapore Institute of Technology; Singapore; On-site; SGD 60,000 - 85,000; Full time

Job summary

Singapore Institute of Technology is looking for a Research Fellow / Research Engineer specializing in biosensor and microbial detection. This role involves delivering industry innovation research projects related to microbial characterization using cutting-edge sequencing workflows. Candidates should possess at least a Bachelor's degree in a relevant field and have hands-on experience with next-generation sequencing technologies. The position also requires strong laboratory skills and the ability to manage projects effectively.

Qualifications

• Hands-on experience with next-generation sequencing technologies.
• Demonstrated experience working with environmental or low-biomass microbial samples.
• Demonstrated experience performing qPCR assays for nucleic acid quantification.

Responsibilities

• Deliver an industry innovation research project on microbial detection.
• Plan and execute experimental workflows for microbial detection.
• Prepare technical reports and contribute to scientific publications.

Skills

Next-generation sequencing technologies

Molecular biology techniques

Experimental design

Strong scientific communication

Education

Bachelor’s degree in Molecular Biology, Microbiology, Biotechnology, or related field

Master’s or PhD degree (advantageous)

Tools

Illumina sequencing

Oxford Nanopore sequencing

Bioinformatics tools

Job description

Job Description

Research Fellow / Research Engineer (Biosensor and microbial detection) - JP2. The primary responsibility of this role is to deliver an industry innovation research project as part of a research team developing molecular and sequencing workflows for microbial characterization. The work supports the rapid detection of microbial bioburden in biopharmaceutical cleaning validation using a Surface-Enhanced Raman Spectroscopy (SERS) biosensor platform.

Technical Responsibilities

• Perform microbial community characterization using next-generation sequencing (NGS) platforms such as Illumina sequencing or Oxford Nanopore sequencing.
• Design and perform qPCR-based molecular assays for microbial quantification and aptamer validation.
• Prepare DNA sequencing libraries, including nucleic acid extraction, amplification, and library preparation.
• Conduct basic bioinformatics processing of sequencing data, including sequence quality control and taxonomic profiling where required.
• Support aptamer discovery and validation experiments, including nucleic acid preparation, amplification, and molecular characterization.
• Perform routine molecular biology techniques such as PCR, gel electrophoresis, DNA purification, and nucleic acid quantification.
• Maintain accurate laboratory records and experimental documentation.

Research & Project Responsibilities

• Plan and execute experimental workflows to support project milestones related to microbial detection and biosensor development.
• Contribute to sequencing-based microbial profiling of environmental and cleaning validation samples.
• Work collaboratively with project investigators and interdisciplinary teams to integrate sequencing and molecular biology results with biosensor development.
• Prepare technical reports and contribute to scientific publications, presentations, and project documentation.
• Support generation of experimental data required for project validation and milestone reporting.

Operational Responsibilities

• Ensure laboratory compliance with Work Safety and Health (WSH) regulations and institutional safety guidelines.
• Manage procurement and inventory of molecular biology and sequencing consumables.
• Maintain laboratory equipment used for molecular biology and sequencing workflows.

Mentorship

• Support training of junior researchers, research assistants, and students where required.
• Contribute to knowledge sharing within the research group.
• Communicate with internal or external stakeholders to ensure project deliverables are met.
• Any ad-hoc duties assigned by Supervisor.

Job Requirements (Essential)

• Bachelor’s degree in Molecular Biology, Microbiology, Biotechnology, Bioengineering, or a related field. Possessing a Master’s or PhD degree will be advantageous.
• Hands‑on experience with next‑generation sequencing technologies, such as Illumina or Oxford Nanopore sequencing platforms including sequencing library preparation.
• Demonstrated experience working with environmental or low‑biomass microbial samples.
• Demonstrated experience with DNA extraction and PCR amplification.
• Demonstrated experience performing qPCR assays for nucleic acid quantification and molecular analysis, including troubleshooting.
• Demonstrated experience with aptamer technologies or nucleic acid‑based molecular recognition systems.
• Strong laboratory skills in molecular biology techniques.

Preferred Qualifications

• Familiarity with microbial community sequencing workflows such as 16S rRNA sequencing or metagenomic analysis.
• Demonstrated experience with bioinformatics tools for sequencing data processing (e.g., quality control, taxonomic classification, microbial community analysis).
• Demonstrated experience working in interdisciplinary or industry‑linked research projects.

Key Competencies

• Strong experimental design and troubleshooting skills in molecular biology.
• Ability to independently conduct laboratory experiments and manage datasets.
• Strong scientific communication skills, including technical reporting and presentations.
• Ability to collaborate effectively with multidisciplinary research teams.
• Good organizational and project management skills.