Senior Scientist, Targeted RNA Delivery & Bioconjugation

Singular: Building Brilliant Biotechs

Singapore

On-site

SGD 90,000 - 120,000

Full time

14 days+
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Job summary

Singular: Building Brilliant Biotechs in Singapore is seeking a Senior Scientist, Bioconjugation & Targeted RNA Delivery to advance LOC-based therapies. The role is laboratory-based with strong ownership and cross-functional collaboration to push delivery performance beyond the liver.

The ideal candidate will have a PhD in a relevant field and 2–6 years of industry experience in bioconjugation or oligonucleotide therapeutics, with hands-on synthesis and analytical characte risation expertise.

Qualifications

  • PhD required in a relevant chemistry/biology discipline.
  • 2–6 years of industry experience in bioconjugation, targeted delivery or oligonucleotide therapeutics.
  • Strong expertise in conjugation chemistry, purification and analytical characterisation.

Responsibilities

  • Design and develop ligand-oligonucleotide conjugates (LOCs) for targeted RNA delivery.
  • Lead hands-on synthesis, purification and analytical characterisation of novel conjugates.
  • Work closely with chemists, biologists and pharmacologists to optimise in vitro and in vivo delivery performance.
  • Drive project execution, manage external partners and maintain high-quality experimental data.

Skills

Bioconjugation chemistry
Targeted delivery
Oligonucleotide therapeutics
Analytical characterisation

Education

PhD in Chemistry, Chemical Biology, Medicinal Chemistry or related

Job description

Singular: Building Brilliant Biotechs in Singapore is seeking a Senior Scientist, Bioconjugation & Targeted RNA Delivery to advance LOC-based therapies. The role is laboratory-based with strong ownership and cross-functional collaboration to push delivery performance beyond the liver.

The ideal candidate will have a PhD in a relevant field and 2–6 years of industry experience in bioconjugation or oligonucleotide therapeutics, with hands-on synthesis and analytical characte risation expertise.

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