Senior Genomics Cloud Platform Engineer

ILLUMINA INTERNATIONAL GENOMICS PTE. LTD.; Singapore; On-site; SGD 180,000 - 260,000; Full time

Job summary

Illumina International Genomics Pte. Ltd. in Singapore seeks a Senior Staff Software Engineer to transform state-of-the-art analytic methods into scalable, high-performance software.

You will work across bioinformatics, cloud infrastructure, and product management, prototyping quickly and delivering a releasable product with a globally distributed team. The role emphasizes designing scalable pipelines, APIs, and interfaces for data-heavy genomics applications, with leadership to raise

Qualifications

• Degree in Computer Science / Engineering / Bioinformatics / Mathematics or a related field.
• Experience designing and delivering large-scale, data-analysis production software in the cloud (AWS, Azure, or GCP), including containerization (Docker), orchestration, infrastructure automation, and CI/CD.
• Strong experience with modern data lake/lakehouse architectures, including Iceberg or Delta Lake table specifications, catalog services, snapshot lifecycle, partitioning and pruning strategy, compaction, and schema evolution.
• Proficiency in Python for rapid prototyping, data analysis, and productionized tooling, with familiarity with the scientific and ML/DL library ecosystem.
• Experience designing and operating distributed batch and workflow systems that manage very large numbers of concurrent jobs, including metrics, tracing and structured logging, retry, checkpointing and idempotency, and failure triage at million-task scale.
• Experience with scientific workflow languages and engines (e.g., Nextflow, WDL, CWL) and with execution on cloud batch or Kubernetes.
• Experience designing and delivering service APIs with an API-first approach: REST or gRPC interface design, versioning and backward compatibility, and multi-tenant access patterns; plus front-end familiarity for data-heavy scientific apps.
• Proven technical leadership and ability to self-manage and lead interdisciplinary relationships.

Responsibilities

• Turn advanced statistical genetics methods into high-performance, scientifically accurate products.
• Design and implement analysis pipelines that scale to millions of samples on a cloud-native lakehouse.
• Deliver APIs, web UI and query interfaces for interactive exploration of results and data.
• Own operability and economics of the platform, ensuring fault tolerance and reproducibility at scale.
• Collaborate with scientists, infra teams and product management to translate needs into a credible delivery plan.
• Set technical direction and raise engineering standards through design reviews and mentorship.

Skills

Python

C/C++

Communication

Cloud computing

Education

Bachelor's degree in Computer Science / Engineering / Bioinformatics / Mathematics

Tools

Docker

Kubernetes

Apache Iceberg

Delta Lake

Parquet

Spark

Trino

Databricks

Job description

Illumina International Genomics Pte. Ltd. in Singapore seeks a Senior Staff Software Engineer to transform state-of-the-art analytic methods into scalable, high-performance software.

You will work across bioinformatics, cloud infrastructure, and product management, prototyping quickly and delivering a releasable product with a globally distributed team. The role emphasizes designing scalable pipelines, APIs, and interfaces for data-heavy genomics applications, with leadership to raise