Research Scientist (SXY Lab), IMCB

A*STAR - Agency for Science, Technology and Research; Singapore; On-site; SGD 70,000 - 90,000; Full time

Job summary

A leading research organization in Singapore seeks a skilled researcher with a PhD in Biology or related field. The role involves developing stem cell-derived retinal cells for therapeutic screening and requires expertise in cellular and molecular techniques. Candidates should have a strong background in stem cell biology and experience in disease modeling. The position is perfect for those who enjoy collaborative research and have a track record in scientific writing and publications.

Qualifications

• PhD in a relevant field or equivalent experience is required.
• Experience in epithelial or vascular endothelial differentiation is preferred.
• Ability to design and analyze complex experiments.

Responsibilities

• Develop human stem cell-derived retinal cells for therapeutic screening.
• Evaluate therapeutic uptake and efficiency with advanced assays.
• Collaborate with a multidisciplinary team on research output.

Skills

Stem cell biology

Cellular techniques

Molecular techniques

Scientific writing

Education

PhD in Biology, Biomedical Science, Biotechnology

Tools

qPCR

Immunofluorescence

Confocal microscopy

Flow cytometry

Job description

Job Description

• Develop and apply human stem cell-derived retinal epithelial and endothelial cells for therapeutic screening.
• Evaluate therapeutic uptake, trafficking, and knockdown efficiency using advanced molecular and cellular assays.
• Build and apply functional assays (e.g. migration, tube formation) to assess therapeutic outcomes.
• Test lead candidates in preclinical mouse models, evaluating biodistribution and efficacy through various delivery routes.
• Collaborate with a dynamic, multidisciplinary team, contributing to publications, presentations, and translational milestones.
• Drive reporting outputs including progress updates, invention disclosures, and final research reports.

Job Requirements

• PhD in Biology, Biomedical Science, Biotechnology, or related field (or equivalent experience).
• Strong background in stem cell biology, with experience in epithelial or vascular endothelial differentiation is preferred.
• Expertise in cellular and molecular techniques (e.g. qPCR, immunofluorescence, confocal microscopy, flow cytometry).
• Experience in in-vitro and in-vivo (rodent) disease modelling is highly preferred.
• Proven ability to design, execute, and analyze complex experiments with attention to detail.
• Strong communication skills and a collaborative mindset, with a track record of scientific writing or high impact publication.