Purification Development Lead Scientist

Lonza; Singapore; On-site; Confidential; Full time

Benefits offered by this job

Medical insurance

Family coverage option

Transport to Tuas site

Global exposure and growth

Job summary

Lonza Singapore seeks a Lead Scientist in Purification Development to lead downstream process development and characterization for recombinant protein production. You will oversee chromatography, UF/DF, resin reuse, and DoE studies while guiding a team and collaborating across functions.

The role supports regulatory submissions and manufacturing transfers with a focus on scientific excellence. You will mentor junior scientists, prepare technical documentation, and act as project representative

Qualifications

• Degree/PhD in Life Sciences or related field.
• 4–7 years' protein purification/process development experience.
• Strong protein purification and Process Characterization expertise.
• Experience with DoE data analysis; JMP is advantageous.
• Understanding of cGMP/BLA requirements preferred.
• Strong technical writing and communication skills.
• Good team player with cross-project collaboration.

Responsibilities

• Lead and oversee Process Development, Process Characterization, and viral clearance activities; study planning and interpretation.
• Drive small-scale model studies: risk assessments, DoE, scale-down qualification, resin lifetime studies; support regulatory submissions.
• Lead purification activities using chromatography (Affinity, Mixed-Mode, Ion Exchange) and UF/DF; support viral reduction studies.
• Train and mentor junior scientists in purification technologies and lab techniques.
• Prepare and review protocols, reports, SOPs, and technical docs.
• Coordinate multiple projects with internal/external stakeholders for timely delivery.
• Provide tech support for manufacturing operations, troubleshooting, and tech transferInitiatives.
• Contribute to scientific excellence, safety, and training.

Skills

Protein purification

Process development

Data analysis

Technical writing

Team collaboration

Education

PhD in Life Sciences

Tools

ÄKTA/UNICORN systems

Job description

Lonza Singapore seeks a Lead Scientist in Purification Development to lead downstream process development and characterization for recombinant protein production. You will oversee chromatography, UF/DF, resin reuse, and DoE studies while guiding a team and collaborating across functions.

The role supports regulatory submissions and manufacturing transfers with a focus on scientific excellence. You will mentor junior scientists, prepare technical documentation, and act as project representative