Project Management Manager

Westrama Management (S) Pte Ltd; Singapore; On-site; SGD 120,000 - 160,000; Full time

Job summary

Westrama Management (S) Pte Ltd is seeking a Project Manager – Process Packages for Drug Substance. You will lead end-to-end packages from design through commissioning, ensuring GMP compliance, quality, budget, and schedule while coordinating with internal teams and vendors.

You will oversee process, mechanical, piping, electrical, automation, and validation activities, manage RFQs, FAT/SAT, and ensure smooth handover to operations with strong stakeholder engagement.

Qualifications

• Master’s degree in mechanical or industrial engineering.
• 8–10 years of pharma/biotech project execution experience.
• Strong GMP, validation and pharma regulatory knowledge.
• Proficiency with MS Project or Primavera and related engineering tools.

Responsibilities

• Develop and manage project execution plans for drug substance process packages.
• Coordinate with process, mechanical, piping, electrical, automation and validation teams.
• Review PFDs/P&IDs, datasheets, and ensure GMP compliance throughout.
• Manage vendor RFQs, FAT/SAT, budgets, and change control.
• Oversee installation, commissioning, IQ/OQ, and project handover to operations.

Skills

Project Management

Leadership

Cross-Functional Collaboration

Stakeholder Management

Education

Master’s degree in mechanical or Industrial Engineering

Tools

MS Project

Primavera

Revit

CAD

Navisworks

Job description

Project Manager – Process Packages (Drug Substance)

Responsible for managing the design, procurement, installation, commissioning, and qualification of pharmaceutical process packages related to drug substance (API/Biotech) facilities. Ensures project execution aligns with GMP standards, budget, schedule, and quality expectations while coordinating with internal teams, vendors, and stakeholders.

Key Responsibilities:

1. Project Planning & Execution

• Develop and manage project execution plans for drug substance process packages (e.g., upstream/downstream, CIP/SIP, buffer prep, chromatography skids).
• Define project scope, timelines, milestones, and deliverables.
• Lead project reviews, risk assessments, and progress tracking.

2. Design & Technical Coordination

• Review and approve PFDs, P&IDs, layouts, and datasheets for package systems.
• Coordinate with process, mechanical, piping, electrical, automation, and validation teams.
• Ensure design compliance with GMP, GEP, and global engineering standards.

3. Vendor & Procurement Management

• Prepare technical specifications, RFQs, and evaluate vendor bids.
• Manage supplier design, FAT/SAT, and package integration to site utilities.
• Control project budgets, contracts, and change management.

4. Construction & Commissioning

• Oversee installation, commissioning, and qualification (IQ/OQ) of drug substance packages.
• Interface with CQV, operations, and QA for system handover.
• Ensure safe execution of site activities as per EHS requirements.

5. Stakeholder Management & Reporting

• Serve as primary point of contact between engineering, procurement, QA, validation, and operations.
• Present regular project updates to management and cross-functional stakeholders.
• Drive issue resolution and maintain strong vendor relationships.

Qualifications:

• Master’s degree in mechanical or Industrial Engineering
• Minimum 8–10 years of experience in pharma/biotech project execution orengineering.
• Strong understanding of GMP, validation, and pharma regulatory requirements.
• Proficient in project management tools (MS Project, Primavera) andengineering software.
• Excellent communication, coordination, and stakeholder management skills.

Skills and Tools

• Experience in EPCM environments or capital projects in Pharma industries
• Experience in Green field projects & Brownfield Projects
• Project Planning (MS Project or Primavera)
• Familiar in Piping & Package 3D Integration(Revits, CAD works or Navis work)
• Engineering Documentation
• FAT/SAT Management
• Cross-Functional Leadership
• Vendor Management
• Risk & Cost Control