Cancer Research Fellow: Organoids & Immunotherapy Studies

Singapore General Hospital Pte Ltd.; Singapore; On-site; SGD 60,000 - 90,000; Full time

Job summary

Singapore General Hospital Pte Ltd. is seeking a highly skilled researcher to plan and conduct experiments for a study on combination therapy in colorectal cancer.

You will work closely with the PI to design and troubleshoot experiments, establish cancer cell models and organoids, and evaluate treatment responses using flow cytometry, IHC, and related assays. You will coordinate sample logistics, maintain meticulous records, and contribute to manuscript preparation while ensuring safety,

Qualifications

• Master's or PhD degree in Life Sciences or a related field (or equivalent experience), with proficiency in experimental design and strong hands-on laboratory skill.
• Proficient in the culture and co-culture of mammalian and immune cells, with practical expertise in maintaining cell lines and optimizing co-culture systems.

Responsibilities

• Plan, execute, troubleshoot experiments with the PI and study team.
• Establish and maintain genetically modified cancer cell models and organoids, including passaging, QC, and banking.
• Conduct cancer-immune cell co-culture and evaluate responses using flow cytometry, Luminex, ELISA, IHC, and microscopy.
• Coordinate with collaborators on sample logistics, timelines, and data sharing.
• Maintain accurate records and present updates to the PI and team.
• Manage laboratory operations (inventory, ordering, equipment maintenance) and ensure biosafety compliance.
• Prepare progress reports for lab meetings and conferences.
• Contribute to manuscript preparation.
• Oversee daily lab operations ensuring safety and compliance.

Skills

Experimental design

Cell culture

Organoid culture

Flow cytometry

Molecular techniques

Team collaboration

Education

Master's or PhD in Life Sciences or related field

Tools

PCR/qPCR

Cloning

Transfection

Western blotting

Job description

Singapore General Hospital Pte Ltd. is seeking a highly skilled researcher to plan and conduct experiments for a study on combination therapy in colorectal cancer.

You will work closely with the PI to design and troubleshoot experiments, establish cancer cell models and organoids, and evaluate treatment responses using flow cytometry, IHC, and related assays. You will coordinate sample logistics, maintain meticulous records, and contribute to manuscript preparation while ensuring safety,