Biomarker Discovery Research Officer

Mirxes; Singapore; On-site; SGD 42,000 - 66,000; Full time

Job summary

MiRXES Lab is seeking a Research Officer to join the Profiling and Sequencing team. The role will assist in developing and executing protocols and SOPs to enable high-quality data from precious clinical samples.

The incumbent will perform high-throughput biomarker discovery experiments, including miRNA RT-qPCR profiling, NGS workflows, and other related techniques, while maintaining robust sample inventories and contributing to technical reports and SOPs.

Qualifications

• Diploma or Degree in a related Science discipline.
• Preferably 2–4 years of molecular biology experience.
• Experience in ELISA, NGS and RT-qPCR is a plus.

Responsibilities

• Execute high-throughput biomarker discovery experiments with clinical samples.
• Perform miRNA RT-qPCR profiling including RNA isolation, reverse transcription and qPCR.
• Run NGS workflows including nucleic acid extraction, library prep and sequencing.
• Work with other technologies either commercially available or in-house.
• Maintain accurate inventory of clinical samples.
• Design, test, and validate protocols for biomarker discovery technologies.
• Collect and organize data for downstream analysis.

Skills

Molecular biology

Teamwork

Communication

Independent work

Education

Diploma/ Degree in a related science discipline

Tools

RT-qPCR

ELISA

NGS

Job description

MiRXES is a Singapore-headquartered molecular diagnostic company with R&D, manufacturing, and clinical lab operations in Singapore, USA, Japan, and China. We specialize in microRNA technologies and the development, manufacturing, and provision of diagnostic test kits and clinical services. Our mission is to enable early disease detection and provide insights for better patient care by harnessing the power of microRNA to augment traditional testing. Our vision is to be the world’s leading developer and provider of accurate, actionable, and affordable microRNA-powered diagnostic tests.

Job Summary

MiRXES Lab is seeking for a Research Officer to join our Profiling and Sequencing team. The biomarker team research officer will assist in development and execution of protocols and SOPs to enable high-quality data to be obtained from precious clinical samples.

Roles and Responsibilities

• Precise execution of experiments for high throughput biomarker discovery using clinical samples.
• miRNA RT-qPCR profiling, including RNA isolation, reverse transcription and qPCR.
• NGS workflows as nucleic acid extraction, library preparation and sequencing.
• Other technologies either commercially available or developed in-house.
• Keep accurate inventory of the clinical samples.
• Perform literature search, design, and conduct experiments for the development, optimization and validation for biomarker discovery technologies.
• Data collection and organization for downstream data analysis.
• Perform other experiments such as ELISA, Western blotting etc. as required to support biomarker discovery
• Write and/or support preparation of technical reports, SOPs and documents.
• Validate procedures for instrument testing, quality control and generate final reports.
• Provide experimental and technical support to internal and external stakeholders whenever necessary.
• Inventory maintenance and procurement of consumables and reagents.
• Provide support for bio-banking activities, if necessary, such as blood processing, sample registration.
• Provide support for compliance of health and safety policies.

Desired Skills and Competencies

• Diploma or Degree in a related Science discipline.
• Preferably with at least 2 - 4 year of molecular biology experience.
• Experience in ELISA, NGS and RT-qPCR experience is a plus.
• Results oriented, with integrity and dependability with a strong sense of prioritization.
• Able to develop in-depth technical related troubleshooting skills and exercise sound judgment and make decisions based on accurate and timely analyses.
• Ability to plan ahead and provide insights and alternatives for contingency.
• Good verbal communication, interpersonal and team skills.
• Demonstrate ability and confidence to work independently as well as within a team.
• Thrive in fast-paced environment where teamwork is essential to success.

This position is based in Singapore.