Senior Project Toxicologist – Immune Safety

AstraZeneca plc; Göteborgs kommun; On-site; SEK 1,000,000 - 1,300,000; Full time

Job summary

AstraZeneca plc in Gothenburg is seeking a motivated Project Toxicologist in Immune Safety to shape safety strategies across target selection, IND-enabling studies, and clinical development. You will join our Immunology Safety team to deliver safe medicines and influence decision-making with cross-functional partners.

The role focuses on designing innovative safety strategies, integrating data from immune assays, NAMs, and translational biomarkers, and mentoring early-career scientists while

Qualifications

• PhD in immunology, toxicology, pharmacology or related discipline.
• Industry experience as a nonclinical safety scientist in immunology or IO.
• Experience delivering toxicology programs to IND and clinical development.
• In vitro/in vivo study design and interpretation, including cytokine release and immunophenotyping.
• Strong regulatory toxicology knowledge and current industry trends.
• Ability to build integrated risk assessments and mitigation strategies.
• Excellent verbal and written communication and collaboration skills.

Responsibilities

• Design, deliver and interpret immune safety strategies across the value chain.
• Lead integrated safety packages using in vitro/in vivo data and NAMs.
• Assess cytokine release, immunomodulation and immunogenicity risks; propose mitigations.
• Deliver GLP toxicology studies, write nonclinical summaries and support submissions.
• Communicate risk positions to project teams and governance bodies.
• Advance predictive immune safety methods and participate in external collaborations.
• Mentor early-career toxicologists and guide external partnerships.
• Evaluate external licensing opportunities and collaboration potential.

Skills

Immunology knowledge

Toxicology expertise

Nonclinical safety

IND/CTA knowledge

Data interpretation

Regulatory toxicology

Scientific communication

Education

PhD in immunology/toxicology/pharmacology

Job description

AstraZeneca plc in Gothenburg is seeking a motivated Project Toxicologist in Immune Safety to shape safety strategies across target selection, IND-enabling studies, and clinical development. You will join our Immunology Safety team to deliver safe medicines and influence decision-making with cross-functional partners.

The role focuses on designing innovative safety strategies, integrating data from immune assays, NAMs, and translational biomarkers, and mentoring early-career scientists while