PostDoc within Neuroscience Discovery Research (all genders) (temporary for 24 months / full-time)

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PostDoc within Neuroscience Discovery Research (all genders) (temporary for 24 months / full-time), Ludwigshafen

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Client:

AbbVie

Location:

Job Category:

Other

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EU work permit required:

Yes

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Job Reference:

1393c9dba4be

Job Views:

2

Posted:

26.05.2025

Expiry Date:

10.07.2025

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Job Description:

People. Passion. Possibilities. Three words that make a world of difference.

More than a job. It's a chance to make a real difference.

Welcome to AbbVie! As part of an international company with 48,000employees worldwide and around 3,000 employees in Germany, you will have the opportunity of addressing some of tomorrows unmet medical needs in close collaboration with your colleagues. Are you passionate about improving global health care? Do you want to contribute to improving patients' quality of life through your expertise? In a challenging work environment that offers opportunities of developing and increasing your own skills? Youve come to the right place!

Together, we break through – as a PostDoc within Neuroscience Discovery Research (all genders) (temporary for 24 months / full-time)

The postdoc position is situated within the Glial Biology Group (Neurodegeneration Research within Neuroscience Discovery Research) in Ludwigshafen, Germany. The Glial Biology team consists of 10 members that together bring forward pre-clinical research to understand the role of glia cells in Alzheimer´s and Parkinson´s disease. The project will run for two years with the potential of getting a third year. Responsible for contributing to the scientific and strategic incorporation of AI/ML tools into existing CDD workflows.

Parkinson's disease (PD) is the second most common neurodegenerative disease. Most PD cases PD are considered idiopathic. However, more than 20 genes have recently been identified that cause monogenic forms of PD. PD was originally thought to predominantly affect dopaminergic neurons, but it is increasingly clear that PD-related mutations cause significant changes in inflammatory cells. This observation aligns with recent genetic studies indicating that, in PD, like Alzheimer's disease, immune dysfunction is causally involved.

Make your mark:

• Systematically analyze the effects of PD-related mutations on the inflammatory profile of CNS immune cells (microglia, astrocytes).
• Evaluate and Analyze patient-derived iPSC lines of mutation carriers in an isogenic comparison to unravel possible inflammatory pathway dysfunctions connected to PD.
• Enable target identification with new mechanisms of action (MOA) for PD disease modification.
• Formal technical and content review of results, analysis data, and reports.
• Consolidate and present scientific activities and results at internal as well as external meetings.
• Creation of lab reports and methods.

This is how you make a difference:

• PhD in neuroscience, cell biology, biochemistry, pharmacology or related field
• Experience with iPSC culture and differentiation.
• Expertise in computational biology and transcriptomic analysis as well as drug discovery would be an advantage.
• Expertise in molecular biology and protein biochemistry including method development and validation would be an advantage.
• High scientific rigor and commitment to provide robust high quality scientific results.
• Very good skills in planning and coordination of complex interdisciplinary studies.
• A high degree of self-initiative, independency, flexibility and curiosity.
• Excellent teamwork, communication and interpersonal relationship skills.
• Language proficiency in English (written and oral).

What we offer you:

• with a diverse work environment where you can have a real impact
• with an open corporate culture
• with an attractive salary
• with an intensive onboarding process with a mentor at your side
• with flexible work models for a healthy work-life balance
• with a corporate health management that offers comprehensive health and exercise programs
• with company social benefits
• with a wide range of career opportunities in an international organization
• with top-tier, attractive development opportunities
• with a strong international network

At multiple times, we have been globally recognized as a "Great Place to Work" and we are proud to provide our employees with the flexibility to maintain a healthy work-life balance. We take our impact on the environment and our communities seriously and therefore focus on giving something back on a regular basis. We are committed to equality, equity, diversity and inclusion (EED&I) – a commitment that is fundamental to us. This includes appreciating different perspectives, creating an inclusive culture and treating all employees with dignity and respect.

At AbbVie, your individual contributions count – help us move mountains together. Be a part of our success, grow with us and accomplish more than you could have imagined. Sounds like the perfect career opportunity for you? We look forward to receiving your application! All you need is a complete CV – we will discuss everything else with you in person.

Any questions? Feel free to email us at [emailprotected] – We look forward to hearing from you!