Master Thesis Project (m / f / d) –Tumor Cell Plasticity Group

Master’s Thesis Project : Scope and Responsibilities

As part of your thesis, you will :

• Apply sequencing-based molecular biology techniques (e.g., RNA-seq, ChIP-seq, HiChIP, Hi-C, PRO-seq) to investigate gene regulation and epigenetic mechanisms in cancer.
• Perform bioinformatic analysis and interpretation of high-throughput data to generate and test biological hypotheses.
• Conduct advanced cell culture experiments, including drug treatment studies in diverse cancer models.
• Use CRISPR / Cas9 gene editing to generate and analyze genetically modified cell lines.
• Participate in high-throughput compound screening in engineered models.
• Engage in internal and external collaborative research projects.
• Document experimental protocols, data acquisition, and analysis results systematically.

Qualifications

We are looking for a highly motivated Master’s student who :

• Is currently enrolled in a Master of Science program (e.g., Biology, Molecular Biology, Molecular Medicine, or a related field).
• Has practical experience with cell culture, transfection techniques, and standard molecular biology methods (e.g., qPCR, Western blotting).
• Possesses a basic understanding of sequencing data and a strong interest in bioinformatics and data-driven biology.
• Works independently, is goal-oriented, well-organized, and thrives in a team environment.
• Communicates confidently in written and spoken English.
• Is passionate about contributing to cancer research and making a meaningful impact.
• Non-EU applicants will only be considered if they have already secured funding for their stay

Additional Information

What We Offer :

• A dynamic and international research environment
• Extensive expertise in cutting-edge epigenetic and gene regulatory techniques
• Access to robust bioinformatics support
• State-of-the-art infrastructure for project-related methods
• A collaborative and supportive lab culture
• Long-standing expertise in cancer biology and transcriptional regulation ( https : / / pubmed.ncbi.nlm.nih.gov / ?term=najafova+z&sort=pubdate&size=20 )

Group Leader Tumor Cell Plasticity Group