PhD Project "Cardiac chromatin biology" (Gilsbach_0125) - Heidelberg University

HBIGS Heidelberg Biosciences International Graduate School

Organisation/Company HBIGS Heidelberg Biosciences International Graduate School Department Dept. for Biosciences Research Field Biological sciences » Biology Researcher Profile First Stage Researcher (R1) Positions PhD Positions Country Germany Application Deadline 31 Jul 2025 - 23:55 (Europe/Berlin) Type of Contract Temporary Job Status Full-time Hours Per Week 40 Offer Starting Date 1 Aug 2025 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

We are seeking a highly motivated and creative PhD candidate to join the Gilsbach lab (gilsbachlab.de) at Heidelberg University, ranking among the top three universities in Germany. The PhD position is fully funded with a competitive salary (TVL-13, 65%).


The available research projects aim to understand and develop strategies to treat heart disease. You will combine epigenetic (e.g. C&T, ChIP-seq, ATAC-seq), chromatin interaction analysis (Hi-C) and single-cell approaches to unravel regulatory mechanisms of heart function and disease, including the impact of disease-associated non-coding variants. CRISPR-based functional genomics will allow you to explore and steer the regulatory mechanisms of heart disease. These studies will take advantage of in vitro and in vivo pre-clinical models, including hiPSC-derived systems.

• MSc degree in molecular biology, epigenetics, cardiovascular science, computational biology, or a related field
• A strong interest in chromatin biology, gene regulation, and/or disease modeling
• Prior experience with genomics, bioinformatics, or CRISPR technologies is a plus, but not mandatory

Languages ENGLISH Level Good

Additional Information

The lab is located at the Institute of Experimental Cardiology in a new research building with cutting-edge facilities hosting several cardiovascular research groups forming a highly interactive and dynamic research infrastructure.

Number of offers available 1 Company/Institute University Hospital Heidelberg, Internal Medicine VIII, Inst. Experimental Cardiology Country Germany City Heidelberg Postal Code 69120 Street Im Neuenheimer Feld 669 Geofield