PhD candidate (f/m/x) –Gene therapy

PhD candidate (f/m/x) – Gene therapy

We are Helmholtz Munich. In a rapidly changing world, we discover breakthrough solutions for better health.

Our research is focused within the areas of metabolic health/diabetes, environmental health, molecular targets and therapies, cell programming and repair, bioengineering, and computational health. We particularly excel in the fields of basic research, bioengineering, artificial intelligence, and technological development.

This is what drives us. Why not join us and make a difference?

The Institute of Experimental Genetics (IEG) aims to further the understanding of mechanisms underlying human diseases' etiology. Metabolic diseases with a focus on diabetes are key areas of research. Experimental set-ups are centered on the mouse as a pre-clinical model organism with direct translation of results to humans.
The group Functional Genetics investigates molecular pathways and pathophysiological events that lead to diabetes and transfer the results into the development of novel strategies for diagnosis, prevention and therapy. As part of our focus on monogenic forms of diabetes, we offer talented candidates (f/m/x) the opportunity to start an exciting PhD project in performing gene therapy on mouse models and evaluating their therapeutic efficacy by in-depth phenotyping.

Your tasks

• Cell culture: In vitro evaluation of gene therapy strategy
• Animal handling: Transfer of gene therapy products to target tissues and evaluation of their therapeutic efficacy by systemic phenotyping (in collaboration with the German Mouse Clinic)
• Histology: Morphometric analysis of target organs
• Omics technology: Comparative transcriptome and proteome analysis

Your profile

• Appropriate university studies (M. Sc.) in biology or related disciplines that qualifies the candidate to unroll as PhD student at the Technical University Munich (TUM)
• Solid background in genetics, molecular and cell biology
• Practical experience with mouse models is highly valued
• Excellent communication skills in written and spoken English

Benefits

• Scientific Training: Helmholtz Munich Graduate School
• Career counseling: Career Center for PhD candidates
• Recreation: 30 days annual leave, flexi days, plus public holidays
• Health Promotion: Sports, company doctor, mental health initiatives
• International Staff Service: Support with the relocation and integration process in Germany

This position provides the opportunity for you to build specialist knowledge whilst developing key professional experience, both of which will help you to make strides in your scientific career.

Remuneration and social security benefits are based on the German Collective Wage Agreement for Public-Sector Employees at Federal Level (EG 13 50% TV EntgO Bund). In addition, there is also the possibility of receiving an allowance if the applicable conditions are met. The position has an (initial) fixed term of three years but may be extended under certain circumstances.

We are committed to promoting a culture of diversity and welcome applications from talented people regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical abilities, religion or age. Qualified applicants with physical disabilities will be given preference.

Interested in applying?

If you have any questions, feel free to contact Dr. Gerhard Przemeck, gerhard.przemeck@helmholtz-munich.de, who will be happy to help.

Your application should include

• CV
• Cover letter
• Degrees/Diplomas/Certificates
• Contact details for at least two referees

Helmholtz Munich
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Institute of Experimental Genetics
Ingolstädter Landstraße 1
85764 Oberschleißheim