Lead HTS Scientist — Large-Scale Drug Discovery

Selvita; Kraków; Hybrid; PLN 260,000 - 420,000; Full time

Benefits offered by this job

Fully automated HTS platform

Professional development

Lunch card

Private medical care

Fruit & wellness program

Job summary

Selvita is seeking an experienced Senior Scientist – High Throughput Screening to join the In Vitro Pharmacology Oncology team in Kraków. You will design, execute, and optimize large-scale HTS campaigns and contribute to assay development, automation, and hit identification.

The role requires a PhD and at least 5 years in biotech/pharma/CRO, with hands-on HTS, biochemical/cell-based assay work, and experience with automated platforms. English fluency is essential.

Qualifications

• PhD in Biology, Biotechnology, Pharmacology, Molecular Biology, Biochemistry, or related life science discipline.
• Minimum 5 years of relevant industrial experience in biotech, pharma, or CRO environments.
• Proven experience leading large-scale HTS campaigns, ideally involving 200,000+ compounds.
• Hands-on experience in biochemical and/or cell-based assay development and optimization.
• Experience with automated liquid handling and screening platforms.
• Strong understanding of HTS assay quality, validation, design, and data analysis.
• Experience with hit identification, confirmation, and profiling workflows.
• Experience with ELN and data management systems.
• Excellent written and verbal English skills.

Responsibilities

• Lead and execute large-scale HTS campaigns in 384- and 1536-well formats, including 200,000+ compounds.
• Define screening strategies, assay requirements, controls, and quality criteria.
• Oversee assays from transfer to hit identification and confirmation.
• Ensure high-quality project delivery aligned with timelines and client expectations.
• Develop, optimize, miniaturize, and validate assays for HTS applications.
• Transfer assays to automated HTS formats and improve robustness.
• Interpret data, troubleshoot issues, and drive assay/screening improvements.
• Mentor junior scientists and supervise staff.
• Collaborate with cross-functional teams and clients.

Skills

HTS leadership

Assay development

Automation & robotics

ELN & data management

English proficiency

Education

PhD in Life Sciences

Tools

Automated liquid handling

Echo acoustic dispensing

HTS platforms & robotics

Job description

Selvita is seeking an experienced Senior Scientist – High Throughput Screening to join the In Vitro Pharmacology Oncology team in Kraków. You will design, execute, and optimize large-scale HTS campaigns and contribute to assay development, automation, and hit identification.

The role requires a PhD and at least 5 years in biotech/pharma/CRO, with hands-on HTS, biochemical/cell-based assay work, and experience with automated platforms. English fluency is essential.