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Roche is seeking a Principal Data and AI Engineer to lead the architectural design, implementation, and optimization of enterprise-grade data infrastructure and advanced AI solutions. You will modernize clinical data generation and submissions content through automated, multi-agent systems and scalable cloud infrastructure.
You will liaise with senior leadership to turn complex data and AI strategies into production-ready platforms, setting engineering best practices and driving CI/CD with
At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.
The Principal Data and AI Engineer leads the architectural design, implementation, and optimization of enterprise-grade data infrastructure and advanced AI solutions (including agentic workflows and RAG systems). In this role, you will modernize clinical data generation and submissions content through automated, high-accuracy multi-agent systems and scalable cloud infrastructure. You will establish engineering best practices, guide cross-functional teams, and liaise with senior business leadership to turn complex data and AI strategies into production-ready platforms.
The Clinical Submission Data and Content Generation & Reuse function focuses on transforming the creation, management, and reuse of clinical data and regulatory submission content through advanced digital capabilities and AI-driven automation. The organization develops structured content management platforms, reusable data and content assets, and intelligent agent ecosystems that support clinical submissions, regulatory compliance, and scientific communication. The team is at the forefront of leveraging Generative AI, Agentic Workflows, Knowledge Graphs, and advanced analytics to improve quality, accelerate submission timelines, and enable data-driven decision-making across the clinical and regulatory landscape.
Education / Experience: Extensive track record leading large-scale data architecture and AI/ML solution deployments in complex environments. Proven track record of leading high-impact projects that shape enterprise-level data infrastructure and developing long-term data and AI architecture strategies. Proven experience optimizing end-to-end latency and retrieval accuracy in production RAG systems or agentic AI solutions. Demonstrated experience contributing significantly to data governance and ensuring the resilience and security of critical data infrastructure. Demonstrated leadership in embedding agile software engineering standards, CI/CD automation, and MLOps/LLMOps frameworks.
Ability to interface directly with senior business leadership to translate business requirements into technical roadmaps and architectural decisions. Proven capability to mentor junior and mid-level engineers, promote strong engineering cultures, and drive technical decision-making. Strong strategic mindset with the ability to influence cross-functional architectural decisions and drive technical excellence.
The expected salary range for this position, based on the primary location of Warsaw Grafit is 228,900.00 PLN - 425,100.00 PLN. Final compensation will be determined by a number of factors, including your skills, experience, qualifications, and location. In addition to base pay, this role may be eligible for a discretionary annual bonus with a target of 20% subject to both individual and company performance. This position also offers an attractive benefits package.
A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let’s build a healthier future, together.
Roche is an Equal Opportunity Employer. We believe it’s urgent to deliver medical solutions right now – even as we develop innovations for the future. We are passionate about transforming patients’ lives. We are courageous in both decision and action. And we believe that good business means a better world. That is why we come to work each day. We commit ourselves to scientific rigor, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow. We are proud of who we are, what we do, and how we do it. We are many, working as one across functions, across companies, and across the world. We are Roche.