Senior Biophysicist - Molecular Interactions

Placements24; Queenstown; On-site; NZD 96,000 - 159,000; Full time

Benefits offered by this job

Health benefits

Retirement plan

Professional development

Job summary

Placements24 invites applications for a Senior Biophysicist to lead experimental investigations into protein-ligand interactions at their Queenstown site. You will design and execute advanced biophysical experiments (SPR, ITC, NMR, X-ray crystallography), analyze data, and develop models in collaboration with chemists, biologists, and pharmacologists.

The role requires a PhD and at least four years of postdoctoral or industry experience, strong data analysis and programming skills, and a track

Qualifications

• Ph.D. in Biophysics, Physics, Chemistry, Biochemistry, or a related field.
• Minimum 4 years of post-doctoral or industrial research experience in experimental biophysics.
• Proven expertise in biophysical characterization techniques (e.g., SPR, ITC, calorimetry, spectroscopy).
• Strong understanding of thermodynamics, kinetics, and statistical mechanics as applied to biological systems.

Responsibilities

• Design and conduct sophisticated experiments to characterize molecular interactions (SPR, ITC, spectroscopy, NMR, X-ray).
• Develop and implement novel biophysical assays to address research questions.
• Analyze data, interpret results, and develop models of molecular mechanisms.
• Collaborate with biochemists, molecular biologists, and pharmacologists on projects.
• Mentor junior researchers and contribute to a collaborative research culture.
• Present findings at internal meetings and conferences; contribute to publications.

Skills

Biophysics expertise

Data analysis

Scientific programming

Team collaboration

Communication

Education

Ph.D. in Biophysics/related

Tools

SPR

ITC

Calorimetry

Spectroscopy

X-ray crystallography

NMR

Python

GraphPad Prism

Job description

About the Role

Our client, a leader in Scientific Research & Development , is seeking a highly qualified Senior Biophysicist to join their dedicated team in Queenstown, Eastern Cape . This role is crucial for investigating the intricate molecular interactions that underpin biological processes. You will employ a range of advanced biophysical techniques to study protein-ligand binding, molecular recognition, and cellular mechanisms. The ideal candidate will possess a deep understanding of physical principles applied to biological systems and a proven track record in experimental biophysics. This position offers a stimulating environment for research, collaboration, and innovation, contributing to breakthroughs in areas such as drug discovery and diagnostics. You will work with state-of-the-art equipment and collaborate with a multidisciplinary team of scientists. Our client is committed to scientific excellence and providing a supportive platform for impactful research within the Eastern Cape.

Key Responsibilities

• Design and conduct sophisticated experiments to characterize molecular interactions using techniques such as SPR, ITC, fluorescence spectroscopy, NMR, and X-ray crystallography.
• Develop and implement novel biophysical assays to address specific research questions.
• Analyze complex biophysical data, interpret results, and develop theoretical models to understand molecular mechanisms.
• Collaborate with biochemists, molecular biologists, and pharmacologists to advance research projects.
• Troubleshoot experimental setups and resolve technical challenges.
• Maintain detailed and accurate experimental records and contribute to scientific reports.
• Present research findings at internal meetings and external scientific conferences.
• Contribute to the preparation of manuscripts for publication in peer-reviewed journals.
• Stay abreast of the latest advancements in biophysics and related fields.
• Mentor junior researchers and contribute to a collaborative and innovative research culture.

Requirements

• Ph.D. in Biophysics, Physics, Chemistry, Biochemistry, or a related field.
• Minimum of 4 years of post-doctoral or industrial research experience in experimental biophysics.
• Proven expertise in one or more biophysical characterization techniques (e.g., SPR, ITC, calorimetry, spectroscopy).
• Strong understanding of thermodynamics, kinetics, and statistical mechanics as applied to biological systems.
• Experience with macromolecular structure determination (e.g., X-ray crystallography, cryo-EM) is a significant advantage.
• Proficiency in data analysis software (e.g., GraphPad Prism, Python) and scientific programming.
• Excellent problem-solving skills and a rigorous scientific approach.
• Strong written and verbal communication skills, with experience presenting complex scientific data.
• Ability to work independently and effectively within a multidisciplinary team.
• Demonstrated ability to contribute to impactful research projects.

Benefits

Our client offers a competitive salary, comprehensive health and wellness benefits, and retirement plan contributions. Researchers benefit from access to advanced laboratory facilities and cutting-edge biophysical instrumentation in Queenstown, Eastern Cape . Opportunities for professional development, including attendance at training courses and conferences, are provided. Our client fosters a culture of innovation and scientific inquiry. Join a leading research organization dedicated to advancing fundamental biological understanding and contributing to new therapeutic strategies.