Researcher in mathematical modelling of hub molecules

Ines Heiland; Tromsø; On-site; NOK 540,000 - 590,000; Full time

Job summary

UiT The Arctic University of Norway in Tromsø invites applications for a two-year-and-three-month MSCA-DN research position in mathematical modelling of hub molecules within the Bioinformatics and Systems Biology Group. The work is affiliated with the Department of Arctic and Marine Biology and the candidate will enroll in the PhD program at UiT.

The project focuses on reconstructing mitochondrial biochemistry with emphasis on hub molecule transport and dynamics, and on developing new metabolic

Qualifications

• Master in biochemistry, biophysics, mathematical biology or similar.
• Strong background in mathematics and Python programming.
• Good understanding of biochemistry.
• Excellent written and oral English.
• Willingness to pursue a PhD and contribute to department development.

Responsibilities

• Reconstruct models of mitochondrial biochemistry focusing on hub molecules.
• Develop metabolic flux analysis approaches to study hub molecules.
• Investigate transport, dynamics and post-translational modifications.
• Collaborate across the network and participate in PhD training.

Skills

Mathematics background

Python programming

Biochemistry knowledge

English proficiency

Team collaboration

PhD ambitions

Education

Master in biochemistry, biophysics, mathematical biology

Tools

AI models experience

Metabolic flux analysis

Mass spectrometry data interpretation

Job description

The position

A temporary position as Researcher in mathematical modelling of hub molecules is available within the Marie Skłodowska-Curie (MSCA-DN) network HubMOL . The position is for a period of two years and three months. It will be affiliated with the Bioinformatics and Systems Biology Group at T he Department of Arctic and Marine Biology at UiT. The candidate will be enrolled in the Ph.D. program at the faculty. The research project will be on mathematical modelling approaches targeting mitochondrial metabolism of hub molecules with focus on metabolic flux analysis. The workplace is at UiT in Tromsø.

The position's field of Research

The main task of the project will be the reconstruction of models of mitochondrial biochemistry with strong focus on transport and dynamics of hub molecules and related post translational modifications and the development of new approaches for metabolic flux analyses to unravel the impact of changes in hub molecules on protein modification dynamics.

Qualifications

Marie Skłodowska-Curie (MSCA-DN) education program enrollment requirements:

• The candidate must not have completed a PhD.
• The candidate must not have lived, studied or worked for more than12 months in Norway within the last 36 months.
• The candidate should describe his/her motivation to join the project and how his/her prior experience will help to develop the project.
• The position requires to spend several month in other research institutions within the network.

Required qualifications:

• Successfully completed a master in biochemistry, biophysics, or mathematical biology or similar qualification.
• Strong background in mathematics as well as programming experience in Python.
• Good understanding of biochemistry.
• Documented good written and oral proficiency in English language.
• We are looking for a colleague with excellent cooperation skills, and a positive attitude towards collaborative research, education and outreach. The successful candidate must have ambitions for a Ph.D. and be willing to get involved in the ongoing development of their department and the university as a whole.

Additional desirable qualifications, knowledge and experience:

• experience in the use of advanced AI models
• working experience in mathematical modelling of biological pathways beyond the master, especially metabolic flux analysis -
• experience in the interpretation of metabolomics mass spectrometry data

At UiT we put emphasis on the quality, relevance and significance of the research work and not on where the work is published, in accordance with the principles of The San Francisco Declaration on Research Assessment ( DORA ).

We offer

• Good welfare arrangements for employees
• Good career opportunities
• Good arrangements for pension, insurance and loans in the Norwegian Public Service Pension Fund

The remuneration for Researcher is in accordance with the State salary scale code 1108, with a gross annual salary ranging from NOK 540.000,- to 590.000,- in a 100 % position. In special cases a higher salary might be considered. As a state employee, you have one of the best pension schemes availiable. For more informationsee: spk.no .

Norwegian health policy aims to ensure that everyone, irrespective of their personal finances and where they live, has access to good health and care services of equal standard. As an employee you will become member of the National Insurance Scheme which also include health care services.

General information

The appointment is made in accordance with State regulations and guidelines at UiT. At our website, you will find more information for applicants .

After the appointment you must assume that there may be changes in the area of work.

More information about moving to Norway and working at UiT: http://uit.no/mobility

According to the Norwegian Freedom and Information Act (Offentleglova) information about the applicant may be included in the public applicant list, also in cases where the applicant has requested non-disclosure.

In case of discrepancies between the Norwegian and the English version of this description, the Norwegian version takes precedence.