Supply Chain Manager

uniQure; Amsterdam; On-site; EUR 85,000 - 120,000; Full time

Job summary

uniQure is seeking a motivated and hands-on Supply Chain Manager - Clinical Operations to ensure patient-ready supply for AAV gene therapy trials. This on-site role in Amsterdam collaborates with Clinical Operations, TOQ, internal lab teams, and external CDMOs to translate trial plans into reliable daily supply execution.

You will own plans, manage inventory, logistics, labeling, and compliance, delivering end-to-end supply chain performance in a fast-moving gene therapy environment.

Qualifications

• Bachelor’s degree in Supply Chain Management, Life Sciences, Engineering, or related field.
• 5–8 years in biopharma supply chain; ≥3 years in clinical supply chain.
• GMP/GDP/GxP experience; cell and gene therapy/ATMP is a plus.
• Proficiency with ERP and planning tools; experience with IRT is an advantage.
• Strong analytical and collaboration skills.

Responsibilities

• Provide day-to-day on-site supply chain support to internal laboratory and technical operations teams, ensuring timely availability of materials, consumables, and documentation.
• Own clinical supply plans for assigned studies, translating enrollment, visit schedules, and protocol requirements into clear demand and production plans.
• Coordinate clinical logistics and distribution activities, including shipments to depots and sites, temperature-controlled transport, and courier management.
• Manage day-to-day coordination with CDMOs, packaging/labeling vendors, 3PLs, and other supply partners to ensure performance against service levels.
• Maintain accurate master data and supply parameters in ERP and related systems; generate KPIs and drive improvements.

Skills

Clinical supply

GMP/GDP

ERP systems

Data analysis

Cross-functional

Lab coordination

Education

Bachelor in Supply Chain

Tools

ERP systems

Inventory systems

Job description

At uniQure, we are delivering on the promise of gene therapy and delivering hope for patients facing urgent unmet medical needs. Every role in our organization carries profound purpose; whether you're in research, operations, access, or support, your contributions impact patients. We're seeking passionate professionals who thrive in high‑stakes environments, uphold rigorous quality standards, and share our relentless commitment to transforming the lives of patients. Join us in making the impossible possible, where your expertise becomes a catalyst for life‑changing treatments.

uniQure is seeking a motivated and hands‑on Supply Chain Manager - Clinical Operations to help ensure patient‑ready supply for our AAV gene therapy trials. This role is operationally focused and requires consistent on‑site presence in Amsterdam to directly support internal laboratory teams and day‑to‑day supply execution activities. You will play a key role in planning and executing clinical supply activities across planning and scheduling, inventory management, logistics, warehousing, and procurement support in a predominantly outsourced model. Reporting to the Director, Site Head Operations, you will work closely with Clinical Operations, Technical Operations & Quality (TOQ), internal lab teams, external CDMOs, and logistics partners to translate trial plans into reliable, day‑to‑day supply execution. This is a highly visible, cross‑functional role where your work directly supports patients and sites participating in our clinical studies.

Key Result Areas (major Duties, Accountabilities And Responsibilities)

On‑Site Operational Execution & Lab Support

• Provide day‑to‑day, on‑site supply chain support to internal laboratory and technical operations teams, ensuring timely availability of materials, consumables, and documentation
• Execute hands‑on inventory management activities, including goods receipt, stock checks, material issuance to labs, and reconciliation activities
• Maintain physical oversight of site inventory, storage conditions, and material flow within the facility
• Act as the primary on‑site point of contact for urgent supply issues, enabling rapid resolution to avoid disruption to lab and manufacturing activities
• Perform and/or oversee shipment preparation, packing, and dispatch activities in coordination with logistics providers
• Support label control, material traceability, and chain‑of‑identity/chain‑of‑custody requirements where applicable
• Ensure real‑time system updates (ERP/inventory systems) aligned with physical material movements

Clinical Supply Planning & Scheduling

• Establish a fit for purpose sourcing and procurement function, initially focused on TOQ but designed to scale across the wider organization
• Own clinical supply plans for assigned studies, translating enrollment, visit schedules, and protocol requirements into clear demand and production plans
• Develop and maintain supply scenarios and what‑if analyses to manage uncertainty in enrollment, site activation, and patient demand
• Create and update supply schedules with CDMOs and packaging/labeling vendors, ensuring alignment with clinical timelines and key milestones

Logistics & Distribution

• Coordinate clinical logistics and distribution activities, including shipments to depots and sites, temperature‑controlled transport, and courier management
• Prepare and maintain shipment plans and documentation to ensure on‑time, compliant delivery to clinical sites
• Support issue resolution related to shipments, temperature excursions, and site‑level supply questions in collaboration with Clinical Operations and Quality

Procurement & Vendor Coordination

• Support sourcing and procurement activities for clinical supply‑related materials and services (e.g., packaging, labels, shippers, ancillary supplies) in partnership with the Sourcing & Procurement Lead
• Manage day‑to‑day coordination with CDMOs, packaging/labeling vendors, 3PLs, and other supply partners to ensure performance against agreed service levels
• Execute purchase requisitions, purchase order management, and follow‑up directly within ERP systems, ensuring timely ordering and delivery of materials

Operational Excellence, Systems & Compliance

• Maintain accurate master data and supply parameters in relevant systems (e.g., ERP, inventory/supply planning tools, IRT if applicable)
• Generate and interpret supply chain KPIs (e.g., on‑time delivery, backorders, inventory health, lead times) and drive actions to improve performance
• Support continuous improvement initiatives to simplify, standardize, and digitize clinical supply processes.
• Ensure all activities are carried out in compliance with GMP/GDP, SOPs, and study‑specific requirements, partnering with Quality as needed

Cross‑Functional Collaboration

• Serve as a key supply chain partner to Clinical Operations, providing clear visibility on supply plans, risks, and mitigation options
• Participate in study and cross‑functional team meetings, representing clinical supply chain and proactively raising constraints and solutions
• Collaborate with TOQ, Regulatory, and Quality on topics related to labeling, country‑specific requirements, import/export, and change control

Qualifications & Skills

• Bachelor’s degree in Supply Chain Management, Business, Life Sciences, Engineering, or related field (or equivalent experience)
• 5-8 years of relevant experience in supply chain within the biopharma industry, with at least 3 years in clinical supply chain, planning, or clinical logistics
• Experience working in GMP/GDP and GxP environments; cell and gene therapy or ATMP experience is a strong plus
• Solid understanding of clinical trial supply concepts (e.g., demand planning, IRT, labeling/packaging, depots, temperature‑controlled logistics)
• Proficiency with ERP and planning tools; experience with inventory management systems and/or IRT is an advantage
• Strong analytical skills with the ability to translate data into clear decisions and recommendations
• Excellent communication and collaboration skills, comfortable working across functions, time zones, and external partners
• Applicants should be a hands‑on supply chain professional who enjoys owning plans end‑to‑end and seeing your work directly impact patients and sites
• A proactive problem‑solver who can anticipate supply risks, propose options, and follow through on actions
• A strong collaborator who builds trust with Clinical Operations, CDMOs, logistics partners, and internal stakeholders
• Organized and detail‑oriented, yet able to keep sight of the bigger clinical and business picture
• Energized by working in a fast‑moving, innovative gene therapy environment and contributing to uniQure’s mission to transform patients’ lives

uniQure is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, sexual orientation, or gender identity), national origin, age, disability, genetic information, marital status, veteran or military status, or any other characteristic protected by applicable federal, state, or local laws. If you need assistance or a reasonable accommodation during the application process, please contact [e-mail].

uniQure posts all open positions exclusively on our official Careers page and LinkedIn. We do not recruit through any other job boards, third‑party websites, or unsolicited outreach via text or messaging apps. All legitimate communication from uniQure’s Talent Acquisition team will come from an @uniqure.com email address. We will never request financial information nor payment of any kind during the application process. If you receive suspicious outreach claiming to be from uniQure, do not respond or share personal information. Inquiries can be made via [e-mail].

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