Senior Study Operations Leader – Breda (Clinical Trials)

Amgen; Breda; On-site; EUR 90,000 - 120,000; Full time

Benefits offered by this job

Bonus structure

13th month salary

Holiday allowance

Collective health insurance

On-site gym

Restaurant with healthy food

Job summary

Amgen Breda is seeking a Senior Manager Local Study Operations to lead and develop a team of LSOMs, ensuring the timely delivery of the country’s clinical trial portfolio from feasibility through close-out.

You will drive operational excellence by overseeing study execution, portfolio performance, resource planning, and quality, while collaborating with global and local stakeholders to support Amgen’s clinical development strategy. Monthly Breda office presence is expected.

Qualifications

• Degree educated with significant clinical operations experience.
• Around 7 years of experience leading people, teams, projects, or programs within a clinical research environment.
• Proven experience delivering clinical trials within a biotech, pharmaceutical, or CRO setting.
• Experience managing clinical operations across the Netherlands, including strong understanding of local regulatory requirements around global clinical trials.
• Experience overseeing clinical research suppliers (e.g., CROs, central labs, imaging vendors).
• Strong understanding of global clinical trial operations and local regulatory requirements.
• Ability to manage resources, budgets, timelines, and performance metrics.
• Excellent stakeholder management, communication, and cross-functional collaboration skills.
• Continuous improvement mindset with the ability to drive operational excellence and implement best practices.
• Fluency in English and in Dutch.
• Monthly presence in the Breda office.

Responsibilities

• Lead and develop a team of Local Study Operations Managers (LSOMs).
• Oversee the country study portfolio delivery from feasibility to close-out.
• Drive operational excellence by overseeing study execution and portfolio performance.
• Manage resource planning and workload allocation across FTE and FSP teams.
• Monitor portfolio performance, identify risks and quality trends, and lead escalation and mitigation.
• Coordinate with Country-Hub Head and stakeholders to align study strategy.
• Foster continuous improvement and adoption of best practices and digital innovation.

Skills

Leadership

Team management

Clinical operations

Stakeholder management

Cross-functional collaboration

Regulatory knowledge (Netherlands)

English proficiency

Dutch proficiency

Education

Academic degree in relevant field

Job description

Amgen Breda is seeking a Senior Manager Local Study Operations to lead and develop a team of LSOMs, ensuring the timely delivery of the country’s clinical trial portfolio from feasibility through close-out.

You will drive operational excellence by overseeing study execution, portfolio performance, resource planning, and quality, while collaborating with global and local stakeholders to support Amgen’s clinical development strategy. Monthly Breda office presence is expected.