Scientific manager

Johnson & Johnson Innovative Medicine; Leiden; On-site; EUR 69,000 - 120,000; Full time

Benefits offered by this job

Annual bonus

Flexible hours

Home office possibilities

Competitive salary

Job summary

Johnson & Johnson Innovative Medicine Leiden hosts a Scientific Manager Cell and Gene Therapy Analytics role focusing on leading biophysical and separation-based method development for viral vectors and LNP products. You will mentor a 22-person CGTA team and collaborate with process development, quality and regulatory units to advance analytical strategies.

The role emphasizes ownership of method development, data integrity, and communication in English.

Qualifications

• In-depth knowledge of biophysical and separation-based technologies (LC, light scattering, CE).
• Deep scientific insights into (viral) vectors and LNP-based product development.
• Proven people leader experience.
• Direct experience with clinical cell and gene therapy product development and GMP quality systems is preferred.

Responsibilities

• Leads a complementary team developing biophysical and separation technology-based methods.
• Acts as a technical analytical lead to strengthen product development strategy, especially LNP-based products.
• Shares expertise in LC, light scattering and CE and drives method selection and implementation.
• Builds lifecycle management from development to validation for release and characterization.
• Collaborates across multidisciplinary teams and prepares documents for regulatory filing.

Skills

Biophysical analysis

Separation-based tech

Leadership

Team mentoring

Scientific communication

Tools

Liquid chromatography (LC)

Capillary electrophoresis (CE)

Light scattering

Job description

At Johnson & Johnson,we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured,where treatments are smarter and less invasive, andsolutions are personal.Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.Learn more at jnj.com.

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Biotherapeutics R&D

Job Category:

People Leader

All Job Posting Locations:

Leiden, South Holland, Netherlands

Job Description:

For our department in Leiden, we need an ambitious

Scientific Manager Cell and Gene Therapy Analytics

Location: Leiden

Hours: 32-40

Introduction of company and team:

At Johnson & Johnson Innovative Medicine, we are working to build a world without disease. Redefining lives by finding new and better ways to prevent, intercept, treat and cure disease encourages us. We bring together the best minds and pursue the most promising science. We are Johnson & Johnson Innovative Medicine. We collaborate with the world for the health of everyone in it.

Our department

The Cell and Gene Therapy Analytics (CGTA) team is an energetic and dynamic group (22 team members), which is part of Cell and Gene Therapies Analytical Development (CGT AD) Leiden, responsible for developing methods to characterize our (viral) vector products (e.g. based on Adenovirus, AAV, lentivirus and RNA). Together, we use molecular, biological, biophysical and separation-based technologies to assess quantity, potency, purity, and identity characteristics of our products. We have a pivotal role between the process development, quality unit and regulatory authorities.

Responsibilities and Duties:

• Leads a complementary team developing biophysical and separation technology-based methods providing scientific mentor and has a talent for spotting people development opportunities.
• Acts as a technical analytical lead to strengthen our product development strategy, specifically lipid nanoparticle (LNP)-based products.
• Actively shares technical expertise in biophysical and separation-based technologies, such as liquid chromatography (LC), light scattering and capillary electrophoresis (CE) and drives selection and implementation of the most suitable technology.
• Strives to build the life cycle management from development using AQbD principles up to and including validation of methods for release and characterization of our products demonstrating a lean mentality for optimization.
• Enjoys working in a multidisciplinary team and has strong capabilities to collaborate with scientists across multiple teams.
• Takes ownership as author or reviewer in the preparation of presentations, reports and documents for regulatory filing and patents.

Requirements:

• In-depth knowledge with biophysical and separation-based technologies, such as liquid chromatography (LC), light scattering and capillary electrophoresis (CE)
• Deep scientific insights into (viral) vectors and specifically LNP-based product development in pharmaceutical industry
• Confirmed people leader experience
• Preferably also, direct experience with clinical cell and gene therapy product development and/ or method development (according ICH Q2) and quality systems such as GMP

The candidate should have the following skills:

• Proven practical lab skills for biophysical and separation-based technologies
• Pragmatic and passionate in the lab
• Phenomenal teammate
• Outspoken with a can do mentality
• Organizational sensitivity and conflict resolution skills
• Critical thinker valuing accuracy in the execution of your work and that of others
• Excellent written and verbal communication skills in English

We value an ethical working environment, as described in our Credo, where trust, diversity, equity and inclusion is the fundament for success.

Our company offers a broad range of benefits and a competitive salary, as well as flexible hours and home office possibilities.

Contract is for one year with possibility to extend
#DPDS

Required Skills:

Preferred Skills:

Analytical Reasoning, Biochemistry, Chemistry, Manufacturing, and Control (CMC), Clinical Data Management, Clinical Research and Regulations, Clinical Trial Designs, Developing Others, Drug Discovery Development, Inclusive Leadership, Leadership, Molecular Diagnostics, Pharmacovigilance, Process Improvements, Productivity Planning, Quality Assurance (QA), Scientific Research, Team Management, Technical Credibility

The anticipated base pay range for this position is:

€68,600.00 - €119,600.00

Benefits:

In addition to base pay, we offer the following benefits*: an annual bonus with set target (% of pay) depending on pay grade / location, where the actual amount is based on the employees’ and companies’ performance of the previous calendar year, or sales commissions. Moreover, we offer vacation days, parental leave for a minimum of 12 weeks, bereavement leave, caregiver leave, volunteer leave, well-being reimbursement, programs for financial, physical and mental health. We also offer service anniversary and recognition awards, and subject to the terms of their respective plans, employees - and in some location’s eligible dependents - can participate in several insurance plans. For more information, visit Employee benefits | Supporting well-being & career growth | Johnson & Johnson Careers.

*This is for informative purposes only. Amounts and actual benefits may vary by location and are subject to change.