Scientific manager

8852-Janssen Vaccines & Prevention B.V. Legal Entity; Netherlands; On-site; EUR 69,000 - 120,000; Full time

Benefits offered by this job

Annual bonus

Vacation days

Parental leave

Well-being programs

Job summary

Johnson & Johnson Innovative Medicine in Leiden seeks an ambitious Scientific Manager Cell and Gene Therapy Analytics to lead a 22-person team in CGTA Leiden. You will develop and validate methods for viral vectors using LC, CE and light scattering, collaborating across process development, quality, and regulatory affairs.

We value deep analytical expertise, people leadership, and hands-on laboratory skills with GMP experience.

Qualifications

• PhD in analytical chemistry or related life sciences with post-doctoral experience preferred.

Responsibilities

• Lead a 22-person team developing biophysical and separation-based methods.
• Act as analytical lead to strengthen product development strategy for viral vectors.
• Share expertise in LC, light scattering, and CE; drive method selection and validation.
• Oversee lifecycle management from development to method validation for release and characterization.
• Collaborate across multiple teams including process development, quality, and regulatory.

Skills

Biophysical techniques

Separation-based technologies

LC

CE

Lab leadership

English communication

AQbD

GMP knowledge

Education

PhD in analytical chemistry

Master's degree in life sciences

Tools

Liquid chromatography (LC)

Light scattering

Capillary electrophoresis (CE)

Regulatory / GMP knowledge

Job description

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com. As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function: Discovery & Pre-Clinical/Clinical Development Job Sub Function: Biotherapeutics R&D Job Category: People Leader All Job Posting Locations: Leiden, South Holland, Netherlands Job Description: For our department in Leiden, we need an ambitious Scientific Manager Cell and Gene Therapy Analytics Location: Leiden Hours: 32-40

Introduction of company and team: At Johnson & Johnson Innovative Medicine, we are working to build a world without disease. Redefining lives by finding new and better ways to prevent, intercept, treat and cure disease encourages us. We bring together the best minds and pursue the most promising science. We are Johnson & Johnson Innovative Medicine. We collaborate with the world for the health of everyone in it.

The Cell and Gene Therapy Analytics (CGTA) team is an energetic and dynamic group (22 team members), which is part of Cell and Gene Therapies Analytical Development (CGT AD) Leiden, responsible for developing methods to characterize our (viral) vector products (e.g. based on Adenovirus, AAV, lentivirus and RNA). Together, we use molecular, biological, biophysical and separation-based technologies to assess quantity, potency, purity, and identity characteristics of our products. We have a pivotal role between the process development, quality unit and regulatory authorities.

Responsibilities and Duties

• Leads a complementary team developing biophysical and separation technology-based methods providing scientific mentor and has a talent for spotting people development opportunities.
• Acts as a technical analytical lead to strengthen our product development strategy, specifically lipid nanoparticle (LNP)-based products.
• Actively shares technical expertise in biophysical and separation-based technologies, such as liquid chromatography (LC), light scattering and capillary electrophoresis (CE) and drives selection and implementation of the most suitable technology.
• Strives to build the life cycle management from development using AQbD principles up to and including validation of methods for release and characterization of our products demonstrating a lean mentality for optimization.
• Enjoys working in a multidisciplinary team and has strong capabilities to collaborate with scientists across multiple teams.
• Takes ownership as author or reviewer in the preparation of presentations, reports and documents for regulatory filing and patents.

Requirements

• The perfect candidate will have at least 4 years of experience after a PhD degree (or at least 8 years of experience after Master degree) in analytical chemistry or life sciences.
• In general, experience in biophysical and separation-based technologies and a broad comprehension of method development principles for (viral) vector product development is required.
• In particular, the following is required: In-depth knowledge with biophysical and separation-based technologies, such as liquid chromatography (LC), light scattering and capillary electrophoresis (CE) Deep scientific insights into (viral) vectors and specifically LNP-based product development in pharmaceutical industry Confirmed people leader experience Preferably also, direct experience with clinical cell and gene therapy product development and/ or method development (according ICH Q2) and quality systems such as GMP

Candidate Skills

• Proven practical lab skills for biophysical and separation-based technologies
• Pragmatic and passionate in the lab
• Phenomenal teammate
• Outspoken with a can do mentality
• Organizational sensitivity and conflict resolution skills
• Critical thinker valuing accuracy in the execution of your work and that of others
• Excellent written and verbal communication skills in English

We value an ethical working environment, as described in our Credo, where trust, diversity, equity and inclusion is the fundament for success.

Contract is for one year with possibility to extend

The anticipated base pay range for this position is: €68,600.00 - €119,600.00

Benefits

• In addition to base pay, we offer the following benefits*: an annual bonus with set target (% of pay) depending on pay grade / location, where the actual amount is based on the employees' and companies' performance of the previous calendar year, or sales commissions.
• Moreover, we offer vacation days, parental leave for a minimum of 12 weeks, bereavement leave, caregiver leave, volunteer leave, well-being reimbursement, programs for financial, physical and mental health.
• We also offer service anniversary and recognition awards, and subject to the terms of their respective plans, employees - and in some location's eligible dependents - can participate in several insurance plans.

*This is for informative purposes only. Amounts and actual benefits may vary by location and are subject to change.

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/.