Postdoctoral Researcher – Analytical Development for Predicting Biopharmaceutical Function (2 years)

Biopharma Careers; Leiden; Hybrid; EUR 54,000 - 85,000; Full time

Benefits offered by this job

Annual bonus

Vacation days

Flexible working 40% remote

Job summary

Johnson & Johnson in Leiden, The Netherlands, invites a Postdoctoral Scientist to join the Analytical Development (AD) team within DPDS. You will develop LC-MS platforms to study glycosylation in antibody-based biotherapeutics and enable predictive tools for smarter biologic drug development.

You will lead independent projects with mentoring, have a dedicated budget, and opportunities for training and conferences, contributing to publications and collaborations with academia and industry.

Qualifications

• PhD in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, or a related field.
• 0-2 years of postdoctoral experience in academia or industry.
• Hands-on LC-MS, data processing and interpretation experience.
• Strong communication and collaborative skills; track record of publishing.

Responsibilities

• Develop a novel LC-MS analytical platform to analyze glycosylation in antibody biotherapeutics.
• Create an automated data processing workflow for intact-protein level glycosylation analysis.
• Collaborate across departments and with external academic partners.
• Publish results in scientific journals and present at conferences.

Skills

Data analysis & interpretation

Excellent communication skills

Scientific publishing experience

Education

PhD in Analytical Chemistry / Biochemistry / Pharmaceutical Sciences

Tools

LC-MS

Analytical software

Job description

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com.

Job Function:

Career Programs

Job Sub Function:

Post Doc - R&D Product Development

Job Category:

Career Program

All Job Posting Locations:

Leiden, South Holland, Netherlands

Job Description:

Our MISSION and WHO we are: At Johnson & Johnson, we believe health is everything. Our R&D team is driving breakthroughs in healthcare innovation to prevent, treat, and cure complex diseases, delivering personalized solutions that profoundly impact health for humanity. Learn more at https://www.jnj.com/.

You will join the multidisciplinary protein characterization team within Analytical Development (AD) in Johnson & Johnson’s Discovery, Product Development and Supply (DPDS) organization. The Leiden AD team supports development and commercial manufacturing of protein-based products. Our work includes method development, comparability studies, protein characterization, complex investigations, and life cycle management. We also enable technical innovation, lab operations, regulatory filings, automation, and advanced data analytics. Science and innovation drive our work through respectful collaboration and commitment to patients. Our diverse international team includes more than 15 nationalities and varied professional backgrounds. This role offers firsthand experience in bringing products to patients, from development through commercialization.

The IMPACT you will make: You will develop a novel LC-MS analytical platform to better understand how glycosylation drives function in our antibody-based biotherapeutics, enabling predictive tools that support smarter biologic drug development and life cycle management.

• Develop an LC-MS and automated data processing workflow for glycosylation analysis on intact-protein level for multiple biotherapeutics (candidates) including monoclonals, bispecifics, trispecifics.
• Set up a comprehensive toolbox for predicting antibody function based on manufacturing process parameters and quality attributes of our biotherapeutics.
• Collaborate across departments and with external, academic partner institutions to strengthen a multidisciplinary approach to improve our understanding of how biotherapeutic engineering and manufacturing conditions influence their structure-function relationships.
• Publish results in scientific journals and present at international conferences.

• You will pioneer translational research by developing groundbreaking technologies which eventually can benefit thousands of patients worldwide.
• You will be the leader of your own project with a high level of independence, mentored by experienced scientists who have a strong background in both academic and industrial research.
• You will have a dedicated budget and ample opportunities for training and traveling to scientific conferences.
• Johnson & Johnson as one of the top pharma companies worldwide, offers a wide range of growth and career opportunities in both R&D and supply chain. This Postdoc position specifically strives to develop talent and improve multidisciplinary collaborations both internally as well as externally with academic partners.

• PhD in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, or a related scientific field with 0-2 years of postdoctoral experience in academia or industry.
• Hands-on LC-MS, data processing, and interpretation experience.
• Excellent communication skills and a collaborative attitude with eagerness for a multidisciplinary way of working.
• Experience in and enthusiasm for publishing scientific articles in peer-reviewed journals and communicating research results at scientific conferences.

Expected salary range: €53,500.00 - €85,445.00

The position is located in the Bioscience Park in the picturesque city of Leiden, The Netherlands. The Leiden Bioscience Park is the largest in the Netherlands. It is an innovation hub offering networking opportunities, with startups, global companies, and the Leiden University being just around the corner.

Benefits: In addition to base pay, we offer the following benefits*: an annual bonus with set target (% of pay) depending on pay grade / location, where the actual amount is based on the employees’ and companies’ performance of the previous calendar year, or sales commissions. Moreover, we offer vacation days, parental leave for a minimum of 12 weeks, bereavement leave, caregiver leave, volunteer leave, well-being reimbursement, programs for financial, physical and mental health. We also offer service anniversary and recognition awards, and subject to the terms of their respective plans, employees - and in some location’s eligible dependents - can participate in several insurance plans.

We offer flexible working conditions, with the option of up to 40% working from home.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.