Postdoc: Translational Nanomedicine for Cancer Therapy

1000scholars; Nijmegen; On-site; EUR 52,000 - 65,000; Full time

Benefits offered by this job

Holiday allowance 8%

Year-end bonus 8.3%

Irregular hours allowance 47%–72%

176 vacation hours per year

Job summary

Radboudumc is seeking a highly motivated Postdoctoral Researcher to lead a project focused on overcoming resistance in pancreatic cancer and other solid tumors using peptide-based targeting and nanomedicine platforms.

You will design, evaluate, and translate nanoparticle-based delivery systems to reprogram the tumor microenvironment and enhance chemo- and immunotherapy in vitro and in vivo, collaborating across biology, medicine, and bioengineering teams.

Qualifications

• PhD in Cancer Biology, Drug Delivery, Nanomedicine, Molecular Medicine, or closely related discipline.
• Expertise in cancer cell biology, tumoral stroma dynamics, or microenvironment targeted therapy.
• Hands-on expertise in nanomedicine formulation/characterization or targeted delivery systems.
• Solid grounding in molecular biology, flow cytometry, confocal microscopy, and histological/spatial analysis techniques.
• Experience with 3D tissue models (organoids, organ-on-chip, 3D bioprinting).
• Experience with preclinical in vivo oncology models (preferred).
• Strong publication record in peer‑reviewed journals for career stage.
• Excellent problem‑solving, fluent English, collaborative mindset.

Responsibilities

• Design, evaluate, and characterize nanoparticle-based drug delivery systems for stromal modulation.
• Conduct in vitro and in vivo efficacy and biodistribution studies in PDAC models.
• Analyze multi-layered data, prepare manuscripts, and present at international conferences.
• Mentor PhD candidates and junior researchers and contribute to ERC project management.

Skills

Cancer biology

Nanomedicine

Molecular biology

Flow cytometry

Confocal microscopy

3D tissue modelling

Preclinical in vivo models

Publication record

English proficiency

Collaboration

Education

PhD in Cancer Biology, Drug Delivery, Nanomedicine, Molecular Medicine, or related

Job description

Radboudumc is seeking a highly motivated Postdoctoral Researcher to lead a project focused on overcoming resistance in pancreatic cancer and other solid tumors using peptide-based targeting and nanomedicine platforms.

You will design, evaluate, and translate nanoparticle-based delivery systems to reprogram the tumor microenvironment and enhance chemo- and immunotherapy in vitro and in vivo, collaborating across biology, medicine, and bioengineering teams.