PhD: Multisynaptic Dendritic Plasticity in Hippocampus

Radboud Universiteit; Nijmegen; In loco; EUR 36.000 - 45.000; Tempo pieno

Descrizione del lavoro

Radboud University in Nijmegen, Netherlands, invites applications for a PhD position on multisynaptic plasticity in dendrites within the Wierenga lab at the Donders Institute. You will investigate how calcium signals and kinase activity coordinate plasticity across multiple synapses using two-photon uncaging, advanced imaging and biosensors in hippocampal slices.

The project combines electrophysiology, microscopy and molecular approaches, with opportunities to contribute to publications and

Competenze

• Master's degree in life sciences or related discipline.
• Experience in advanced microscopy and/or patch clamp electrophysiology in living brain tissue.
• Interest in intracellular signalling and optical recording methods; programming ability preferred.

Mansioni

• Use two-photon glutamate uncaging in hippocampal slices to study multisynaptic plasticity.
• Employ advanced microscopy and biosensors to trace molecular pathways.
• Collaborate with an international team and contribute to publications; teaching load up to 10%.

Conoscenze

Motivated

Enthusiastic

Critical

Creative

Team-oriented

Formazione

Master's degree in Life Sciences

Strumenti

Advanced microscopy

Single-cell electrophysiology

Matlab/Python programming

Descrizione del lavoro

Radboud University in Nijmegen, Netherlands, invites applications for a PhD position on multisynaptic plasticity in dendrites within the Wierenga lab at the Donders Institute. You will investigate how calcium signals and kinase activity coordinate plasticity across multiple synapses using two-photon uncaging, advanced imaging and biosensors in hippocampal slices.

The project combines electrophysiology, microscopy and molecular approaches, with opportunities to contribute to publications and