Experienced Scientist, In-vivo CAR-T

Johnson & Johnson Innovative Medicine; Leiden; On-site; EUR 85,000 - 120,000; Full time

Job summary

Johnson & Johnson Innovative Medicine seeks an Experienced Scientist, In-vivo CAR-T, to advance LVV drug product formulation from early to late development. On-site in Spring House, PA or Leiden, NL, you will conduct hands-on formulation work and collaborate across multiple functions to ensure scalable, GMP-ready processes.

The role emphasizes cross-functional teamwork, data-driven decision making, and a strong foundation in drug product development for viral vectors, with opportunities to

Qualifications

• B.S. or M.S. in Life Sciences or Chemical Engineering with 2–4 years of relevant experience.
• Experience in formulation development of viral vectors and/or advanced therapies.
• Hands-on lab experience in drug product development of viral vectors.
• Understanding of process scale-up, technology transfer, and GxP.
• Strong problem-solving and data interpretation skills.
• Cross-functional collaboration and proactive, detail-oriented approach.
• Clear communication and ability to manage multiple priorities.
• Preferred: LVV platforms and early/late-stage development exposure.

Responsibilities

• Formulation development and optimization of viral vectors across early and late development stages.
• Hands-on laboratory work including formulation design, optimization, and characterization.
• Analyze and interpret data to support formulation development and decision-making.
• Support formulation robustness activities.
• Contribute to scale-up and manufacturing readiness, including tech transfer to internal sites or CMOs.
• Collaborate cross-functionally with Analytical Development, Statistical, API, MSAT, Quality, Manufacturing, and Regulatory teams.
• Document experimental work and results in accordance with GxP and data integrity requirements.
• Participate in troubleshooting and continuous process improvement.

Skills

Analytical Reasoning

Biochemistry

Chemistry

Manufacturing & CMC

Coaching

Collaboration

Conducting Experiments

Data Quality

Drug Discovery

Molecular Diagnostics

Pharmacogenetics

Report Writing

Research Documents

Scientific Research

Technologically Savvy

Written Expression

Education

B.S. or M.S. in Life Sciences or Chemical Engineering

Job description

At Johnson & Johnson,we believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented, treated, and cured,where treatments are smarter and less invasive, andsolutions are personal.Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.Learn more at jnj.com.

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Biotherapeutics R&D

Job Category:

Scientific/Technology

All Job Posting Locations:

Leiden, Netherlands, Spring House, Pennsylvania, United States of America

Job Description:

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal.

Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com.

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

We are searching for the best talent for an Experienced Scientist, In-vivo CAR-T, to be based on-site in Spring House, PA or Leiden, Netherlands.

Purpose:

The Experienced Scientist will support the formulation development, optimization, and scale-up of lentiviral vector (LVV) drug product formulation early to late-stage development. The role combines hands-on laboratory work with strong cross-functional collaboration to ensure robust, scalable, and GMP-ready processes.

Key Responsibilities:

• Formulation development and optimization of viral vectors e.g., LVV drug product across early and late development stages
• Perform hands-on laboratory work including formulation design, optimization, and characterization
• Analyze and interpret data to support formulation development, optimization, and decision-making
• Support formulation robustness activities
• Contribute to scale-up and manufacturing readiness, including support of technology transfer to internal sites or CMOs
• Collaborate cross-functionally with Analytical Development, Statistical, API, MSAT, Quality, Manufacturing, and Regulatory teams to ensure alignment on formulation strategy and execution of viral vectors
• Document experimental work and results in accordance with GxP and data integrity requirements
• Participate in troubleshooting activities and continuous process improvement initiatives

Qualifications:

Required:

• B.S. or M.S. with 2-4 years of experience in an appropriate scientific discipline (Life Sciences or Chemical Engineering) is required
• Relevant experience in formulation development of viral vectors and/or advance therapies
• Strong hands-on laboratory experience in drug product development of viral vector development and statistics
• Understanding of process scale-up, technology transfer, and GxP principles
• Strong scientific problem-solving and data interpretation skills
• Hands-on, proactive, and detail-oriented approach
• Ability to work effectively in a cross-functional, matrixed environment
• Clear and concise communication skills (written and verbal)
• Ability to manage multiple priorities in a dynamic development environment

Preferred:

• Experience with viral vector platforms, LVV in particular, and/or advanced therapies
• Familiarity with formulation implementation for both early and late-stage development, process validation (e.g., LCPV) and manufacturing support
• Exposure to both early and late-stage development requirements or commercial readiness activities

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center ([e-mail]) or contact AskGS to be directed to your accommodation resource.

Required Skills:

Analytical Reasoning, Biochemistry, Chemistry, Manufacturing, and Control (CMC), Coaching, Collaboration, Conducting Experiments, Data Quality, Drug Discovery Development, Molecular Diagnostics, Patent Applications, Pharmacogenetics, Report Writing, Research Documents, Scientific Research, Technologically Savvy, Written Expression

Preferred Skills:

Analytical Reasoning, Biochemistry, Chemistry, Manufacturing, and Control (CMC), Coaching, Collaboration, Conducting Experiments, Data Quality, Drug Discovery Development, Molecular Diagnostics, Patent Applications, Pharmacogenetics, Report Writing, Research Documents, Scientific Research, Technologically Savvy, Written Expression