Enzyme Engineer: Biocatalysis for Rubber Recycling

Chemstars; Leiden; Presencial; EUR 60 000 - 90 000; Tempo integral

Vantagens oferecidas por esta oferta de emprego

Stock option plan

Resumo da oferta

AKIN is a Dutch biotech company developing a novel enzymatic platform for rubber recycling. We seek a biocatalysis scientist to own enzyme performance at benchtop scale, develop assays, run reaction studies, and coordinate small-scale production in Delft, with strong collaboration alongside our chemical engineer.

The role includes variant screening, integrated process development, partner interface tasks, and strategic input to R&D roadmap and grant reports.

Qualificações

• MSc in biochemistry, biotechnology, life science & technology, or a closely related discipline, with 3-6 years of hands-on experience; or a PhD with up to 3 years of industry experience.
• Hands-on experience with enzyme activity assays, kinetics and reaction optimisation.
• Experience expressing and purifying recombinant proteins in bacterial and fungal hosts: cell banking, shake-flask and benchtop bioreactor cultures, affinity purification and SDS-PAGE.
• Structured experimental mindset: design controlled benchtop studies (including DoE), keep clean, reproducible data, and iterate quickly.
• Organised and comfortable working with external partners and several priorities at once, including day-to-day running of a shared lab.
• Fluent English. Dutch is not required.

Responsabilidades

• Enzyme performance ownership: developing robust activity assays and running reaction studies on rubber substrates, covering kinetics, stability and the effect of temperature, pH, enzyme loading and co-solvents.
• Variant screening: testing enzyme variants from our engineering partner and turning the results into clear, decision-ready feedback for the next design round.
• Integrated process development: working with our chemical engineer to connect reaction conditions to product profiles, so that upstream and downstream are developed together.
• Partner interface: specifying enzyme batches and checking incoming lots with our scale-up partner, and preparing samples for and interpreting results from external analytical and materials-testing facilities.
• Small-scale enzyme production: maintaining cell banks and expressing and purifying enzyme variants, from shake flasks to our 2.5 L benchtop bioreactors, in our ML-I lab space, so experiments are always supplied.
• Lab coordination (around 10% of your time): inventory, ordering, equipment upkeep, ML-I records, and keeping lab safety and house rules on track.
• Strategic input: contributing to the R&D roadmap, IP filings and grant reporting.

Descrição da oferta de emprego

AKIN is a Dutch biotech company developing a novel enzymatic platform for rubber recycling. We seek a biocatalysis scientist to own enzyme performance at benchtop scale, develop assays, run reaction studies, and coordinate small-scale production in Delft, with strong collaboration alongside our chemical engineer.

The role includes variant screening, integrated process development, partner interface tasks, and strategic input to R&D roadmap and grant reports.