Remodeling Macrophage Polarization to Boost Immunotherapy

Italian Ministry of Education, University and Research; Italia; On-site; EUR 32,000 - 46,000; Full time

Job summary

Università degli Studi di Napoli Federico II invites applications for a research fellowship focused on FKBP51s splice isoform in tumor-associated macrophages (TAMs) to overcome resistance to immunotherapy in melanoma. The project uses primary immune cells, mouse melanoma models, and patient-derived organoids to identify cellular signatures for patient selection and treatment monitoring.

Eligibility includes European residency and nationality requirements.

Qualifications

• European residency or nationality eligibility as required by the program.
• Strong background in chemistry/biochemistry or related biosciences preferred.

Responsibilities

• Investigate the role of FKBP51s splice isoform in tumor-associated macrophages (TAMs).
• Perform functional assays using primary immune cells, mouse melanoma models, and patient-derived organoids.
• Analyze TAM surface markers to identify signatures for patient selection and treatment monitoring.

Job description

Università degli Studi di Napoli Federico II invites applications for a research fellowship focused on FKBP51s splice isoform in tumor-associated macrophages (TAMs) to overcome resistance to immunotherapy in melanoma. The project uses primary immune cells, mouse melanoma models, and patient-derived organoids to identify cellular signatures for patient selection and treatment monitoring.

Eligibility includes European residency and nationality requirements.