Statistical Science Director

AstraZeneca; India; Hybrid; INR 4,500,000 - 7,500,000; Full time

Job summary

AstraZeneca plc in Bangalore is seeking a Statistical Science Director to lead the statistical strategy across drugs in oncology. You will drive design, analysis and evidence plans, coordinating with global teams to inform decisions that shape regulatory submissions and product value.

The role demands deep biostatistics expertise, leadership of multi-disciplinary teams, and a track record of influencing development programs. A hybrid work setup and international collaboration are available.

Qualifications

• Master's in Statistics or related field; comprehensive understanding of drug development and regulatory standards.
• Significant experience in clinical study design and data analysis.
• Strong communication skills to establish effective collaborations.

Responsibilities

• Set statistical vision and strategy across assets, ensuring coherent design and evidence plans.
• Lead Bangalore region staff delivering statistical contributions and expert support.
• Oversee portfolio delivery from early development through commercialization with high-quality analyses.
• Collaborate with clinical, regulatory, data science, and project management teams to craft integrated plans.
• Engage in regulatory content development and advisory meetings aligning with international expectations.

Skills

Statistical leadership

Biostatistics

Clinical study design

Data analysis

Regulatory standards

Education

Master's in Statistics

PhD in Biostatistics

Job description

Job Title: Statistical Science Director

Career Level - F

Location: Manyata Tech Park, Bangalore

Therapy area: Oncology

Work Type: Hybrid

About AstraZeneca:

AstraZeneca is a global, science-led, patient-focused pharmaceutical company that focuses on the research, development, and commercialisation of prescription medicines. We aim to transform the lives of patients with improved outcomes and a better quality of life. But we're more than one of the world's leading pharmaceutical companies. At AstraZeneca, we're dedicated to being a Great Place to Work.

Introduction to role:

It is an exciting time to join AstraZeneca Oncology. Are you ready to lead statistical strategy that accelerates life-changing medicines to patients? Could you shape how science and data come together to inform bold decisions across global programs? This is your opportunity to drive statistical excellence where it has immediate and tangible impact on development turning points and patient outcomes.

Accountabilities:

• Statistical Leadership: Set statistical vision and strategy across one or more assests, ensuring coherent design, analysis, and evidence generation plans that de-risk development and improve product value.
• Manage a group of staff ensuring delivery of statistical contributions or as a Bangalore region expert support assessments and research within a specialist area of Biostatistics.
• Development Strategy and Decision-Making: Quantify benefit, risk, value, and uncertainty for emerging product profiles, informing go/no-go decisions and shaping registration strategies across phases.
• Portfolio Delivery: Oversee large, complex projects from early development through commercialization, ensuring on-time, high-quality statistical deliverables that align with regulatory and business objectives.
• Cross-Functional Integration: Build and lead multi-skilled teams with clinical, regulatory, data science, and project management partners to craft integrated development plans and compelling narratives.
• Global Technical Stewardship: Provide expert consultation to internal stake-holders worldwide and ensure consistent adoption of statistical standards, methods, and tools across regions.
• Regulatory Engagement: Lead or guide statistical content for regulatory interactions, including briefing books, responses, and advisory meetings, aligning evidence packages with international expectations.
• Innovation and Methods Development: Investigate, develop, and apply modern statistical and quantitative approaches, including adaptive designs, advanced modeling, and real-world data integration, to improve insight, speed, and robustness.
• Quality and Compliance: Ensure all statistical work meets AstraZeneca standards and external regulations, maintaining the integrity of analyses, interpretations, and reporting.
• Information Governance: Drive effective planning, documentation, and communication of statistical strategies, results, and assumptions to enable transparent, auditable decisions.
• Proposal and Vendor Oversight: Oversee statistical assessment of proposals and provide leadership to internal and external statisticians assigned to projects, ensuring proper oversight and alignment to goals.
• External Representation and Networking: Represent AstraZeneca and the Statistics function at external forums, build collaborations with professional and regulatory organizations, and share expertise across the enterprise.
• Continuous Improvement: Lead pivotal initiatives to improve quality, accelerate timelines, reduce cost, and strengthen interpretability of evidence, embedding lessons learned into future delivery.

Essential Skills/Experience:

• Master's in Statistics or a related field; Comprehensive understanding of drug development and commercialization phases; Detailed knowledge of statistical, technical, and regulatory standards; Significant experience in clinical study design and data analysis; Strong communication skills to establish effective collaborations.

Desirable Skills/Experience:

• PhD in scientific field; Recognized expert in biostatistics within the pharmaceutical industry; Extensive knowledge of evolving technical methodologies and international regulatory guidelines.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform