Executive/ Senior Executive - Manufacturing

Laurus Bio; Visakhapatnam; On-site; INR 300,000 - 500,000; Full time

Job summary

Laurus Bio Vizag site seeks a shift-based Manufacturing DSP/USP specialist with 2–5 years of experience in biological product processing. You will oversee downstream and upstream operations, ensure equipment readiness, and maintain GMP-compliant production.

Responsibilities include supervising chromatography, UF/DF, filtration, and lyophilization, ensuring BMR adherence, monitoring process parameters, and coordinating with QC and QA teams to maintain product quality.

Qualifications

• 2–5 years of relevant manufacturing experience.
• BSc or MSc in Life Sciences.
• Working knowledge of GMP/cGMP and safety standards.
• Experience supervising a shift.
• Strong documentation practices and accuracy.

Responsibilities

• Supervise downstream/upstream processing during shift.
• Ensure BMRs follow procedures and cGMP guidelines.
• Monitor process parameters and record data.
• Lead, train and supervise production staff on GMP, safety and equipment operation.
• Coordinate with QA, QC and Engineering for smooth operations.

Skills

DSP/USP operations

cGMP compliance

Team supervision

Quality coordination

Documentation practices

Education

BSc / MSc in Life Sciences

Tools

Chromatography equipment

Filtration systems

Lyophilization equipment

Job description

Manufacturing - DSP/USP

Location - Vizag

Exp - 2 - 5 years

Education - BSc. / MSc.

Salary 3 - 5 LPA

Responsible for downstream/ upstream processing operations during the assigned shift to ensure consistent, efficient, and GMP-compliant production of biological products (e.g., monoclonal antibodies, vaccines, recombinant proteins). The role involves supervising the purification process, ensuring equipment readiness, and maintaining quality and safety standards.

Shift Operations Management

• Supervise all downstream/ upstream production activities, including harvest, filtration, chromatography, ultrafiltration/diafiltration (UF/DF) and lyophilization.
• Ensure batch manufacturing records (BMRs) are followed strictly as per approved procedures and cGMP guidelines.
• Monitor process parameters (flow rates, pressures, conductivity, pH, temperature, etc.) and record data accurately.
• Adhering to cGMP, GDP and safety regulations, FSSAI / ISO / etc. standards in the plant
• Perform in-process checks and ensure timely sampling and coordination with the QC team.
• Oversee batch changeovers and line clearances between operations.

2. Team Leadership & Training

• Lead, train, and supervise production executives, operators, and contract staff during the shift.
• Allocate manpower effectively to ensure smooth workflow and timely batch execution.
• Conduct on-the-job training for team members on GMP, safety, and equipment operation.

3. Equipment & Process Management

• Ensure readiness, cleaning, and sterilization of all DSP equipment (e.g., chromatography, TFF systems, centrifuges, filtration units and lyophilizer.
• Coordinate with Engineering for equipment maintenance, calibration, and troubleshooting.
• Review equipment logs and ensure timely updates in line with GMP compliance.

4. Documentation & Compliance

• Review and verify batch records, logbooks, and cleaning records for accuracy and completeness.
• Ensure compliance with cGMP, GDP (Good Documentation Practices), EHS (Environment, Health & Safety), and company quality standards.
• Identify and report deviations, non-conformances, and assist in root cause analysis and CAPA implementation.
• Support internal and external audits and provide necessary process documentation.

5. Coordination & Communication

• Collaborate with Upstream (USP), QA, QC, Warehouse, and Engineering teams for coordinated production activities.
• Communicate critical process issues, equipment alarms, or safety incidents promptly to the Production Manager.