Downstream Processing Specialist

Thermo Fisher Scientific India Pvt Ltd; Bengaluru; On-site; INR 600,000 - 1,200,000; Full time

Job summary

Thermo Fisher Scientific India Pvt Ltd in Bangalore seeks a Downstream Specialist to support upstream and downstream processing activities. You will perform purification and formulation operations, maintain batch records and equipment logs, and ensure compliance with GMP and safety standards.

Requirements include a Master’s degree in life sciences and 1–3 years of biotech experience, with strong communication and teamwork skills to collaborate across departments.

Qualifications

• Master’s degree in life sciences or related field.
• 1–3 years experience in biotech or related field.
• Plans and coordinates work with minimal direction.
• Familiarity with compliance & regulatory standards.

Responsibilities

• Perform unit operation (Purification and formulation) of Primary, Secondary, and polyclonal based on the production schedule and complete as per schedule.
• Fill batch records online and update equipment log books, report routing hours and material issuance daily.
• Follow the company’s quality guidance to ensure product quality.
• Respond to changing priorities and manage multiple projects with overlapping requirements.
• Report deviations or non-deviations to supervisors and ensure GMP/safety compliance.
• Aim for continuous improvement via Kaizen, JDI or related methods.

Skills

Biotech methods

Chromatography

Immunology

Team collaboration

Education

Master’s degree in Life Science

Tools

HPLC

SDS-PAGE

SEC

Protein purification

Job description

Manufacturing Scientist Work Schedule Standard (Mon-Fri) Environmental Conditions Adherence to all Good Manufacturing Practices (GMP) Safety Standards Job Description

About Thermo Fisher Scientific Thermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue of approximately $40 billion. Our Mission is to enable our customers to make the world healthier, cleaner and safer. Whether our customers are accelerating life sciences research, solving complex analytical challenges, growing efficiency in their laboratories, improving patient health through diagnostics or the development and manufacture of life-changing therapies, we are here to support them. Our distributed team of more than 100,000 colleagues delivers an outstanding combination of innovative technologies, purchasing convenience and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services, Patheon and PPD. For more information, please visit www.thermofisher.com .

Job Title: Downstream Specialist

Reports To: Team Leader, Operations

Location: Bangalore

Work Schedule: Standard (Mon-Fri)

Environmental Conditions: Adherence to all Good Manufacturing Practices (GMP) Safety Standards, Office, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.), Will work with hazardous/toxic materials

Purpose: Thermo Fisher Scientific is recruiting a Technical Operations analyst who can develop innovation and improve customer experience by helping the operations team with upstream and Downstream Processing.

Roles and Responsibilities

• Ensure to perform the unit operation (Purification and formulation) of Primary, Secondary, and polyclonal based on the production schedule and ensure to complete as per the schedule.
• Responsible to fill the batch records online and update the equipment log books, report routing hours, material issuance and quantity completion on daily basis.
• Follow the company's dedication to quality by guiding team members of factors that may impact product quality.
• Respond quickly to changing priorities and prioritize different projects at once, with overlapping requirement.
• Ensure to report the deviation or non-deviation compliance to supervisors.
• Responsible to look for continuous improvement in the form of JDI, PPI and Kaizen.
• Responsible to get aligned with 4i Values of Thermofisher Scientific.
• Required to perform tasks as per the need of the hour and/or assigned.
• Strong skills on methodologies and techniques in Biotechnology and Chromatography and Immunology.
• Responsible in providing the information on raw material shortage for Production activities.
• Responsible for experiments to be performed as per Standard Operating Procedures (SOPs).
• Responsible to implement the QC testing's as per the plan within the TAT.
• Responsible in getting trained on data interpretation on driven experiments.
• Responsible for good partnership & team integrity.
• Theoretical or practical experience in antibody Purification and conjugation is desirable.
• Experience and knowledge in protein purification and analysis technologies such as affinity or ion exchange chromatography, SEC, HPLC, and SDS-PAGE.
• Experience with protein affinity measurements and epitope binning is desirable Familiarity or experience in development of conjugation chemistries or performing antibody conjugation.

Other Requirements

Master`s degree/equivalent or relevant in a life science, Biotechnology, Microbiology or related fields

Experience of 1-3 years in the life science/Biotech or relevant field.

Plans and coordinates work with minimal direction.

Familiarity with compliance & regulatory standards

Attention to detail and a dedication to delivering high-quality results.

Strong communication expertise (written & verbal) to optimally communicate technical concepts to diverse collaborators.

Strong interpersonal and time management skills to prioritize and complete tasks.

Requires strong digital literacy, including Microsoft office

Thermo Fisher Scientific is an equal opportunity employer and value diversity at our company. All qualified applicants will receive consideration for employment without discrimination basis race, color, religion, sex, sexual orientation, gender, gender identity or expression, national origin, protected veteran status, age, genetics, pregnancy, disability or any other legally protected status. Thermo Fisher Scientific aligns with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.