Biologist

Quraxia Pharmaceuticals; Haridwar; On-site; INR 600,000 - 1,200,000; Full time

Job summary

Quraxia Pharmaceuticals seeks an Experienced Biologist to join its R&D team to contribute to discovery and development of antibodies, ADCs, and biomarkers for preclinical and translational studies. The role involves hands-on lab work, data analysis, and collaboration with teams in molecular biology, biochemistry, and pharmacology.

Experience in antibody engineering and biomarker assays is valued. You will work on scale-up considerations with process development and CMC teams while maintaining

Qualifications

• Education: MSc / MTech / PhD in Molecular Biology, Biotechnology, Biochemistry, or related life sciences.
• 1–5 years of relevant antibody or ADC research experience (academic or industry).
• Strong hands-on experience in cloning, expression, purification, and assay development.

Responsibilities

• Design, generate, and screen antibodies using hybridoma or recombinant methods.
• Identify and validate antigen targets for therapeutic antibodies.
• Characterize antibodies for specificity, affinity, and stability with biochemical/biophysical assays.
• Express and purify antibodies from mammalian systems and assess in vitro activity.
• Conjugate antibodies with cytotoxic payloads using linker technologies.
• Characterize ADCs for DAR, stability, and potency with analytical and functional assays.
• Develop biomarker assays (ELISA, qPCR, IHC, multiplex) for preclinical/clinical studies.
• Collaborate with cross-functional teams; ensure GLP/GMP and biosafety compliance.

Skills

Molecular cloning

Protein expression & purification

Assay development

Data interpretation & teamwork

ELISA / flow cytometry / SPR

Education

MSc / MTech / PhD in Molecular Biology or related field

Tools

HPLC

LC-MS

ELISA

Flow cytometry

Job description

At Quraxia, we’re building a next-generation pharmaceutical R&D and innovation ecosystem — dedicated to discovering, developing, and delivering breakthrough therapies that improve patient outcomes. Our newly established state-of-the-art facility is designed to foster cutting‑edge science, collaborative innovation, and ethical excellence in every project we undertake.

Role Overview

We are seeking an Experienced Biologist to join our growing Research and Development Team. The Biologist will contribute to the discovery and development of therapeutic monoclonal antibodies (mAbs), antibody–drug conjugates (ADCs), and biomarkers to support preclinical and translational research programs. The role involves hands‑on laboratory work, data analysis, and close collaboration with multidisciplinary teams in molecular biology, biochemistry, and pharmacology.

Key Responsibilities

Monoclonal Antibody (mAb) Development :

• Design, generate, and screen antibodies using hybridoma or recombinant expression technologies.
• Identify and validate antigen targets for therapeutic antibody generation.
• Characterize antibodies for specificity, affinity, and stability using biochemical and biophysical assays (ELISA, SPR, flow cytometry, etc.).
• Express and purify antibodies from mammalian systems and evaluate functional activity in vitro.
• Perform conjugation of antibodies with cytotoxic payloads using optimized linker technologies.
• Characterize ADCs for drug–antibody ratio (DAR), stability, and potency through analytical and functional assays.
• Conduct in vitro efficacy and toxicity studies to evaluate ADC performance.
• Collaborate with process development and CMC teams for scale‑up and optimization.

Biomarker Discovery and Development

• Identify and validate predictive, pharmacodynamic, or diagnostic biomarkers through omics‑based approaches.
• Develop and validate biomarker assays (ELISA, qPCR, IHC, multiplex platforms) for preclinical and clinical studies.
• Analyze biological samples to correlate biomarker expression with therapeutic response.
• Contribute to translational research strategies supporting patient stratification.
• General Responsibilities
• Maintain accurate experimental documentation and prepare technical reports or presentations.
• Collaborate effectively with cross‑functional teams including chemistry, pharmacology, and bioinformatics.
• Ensure compliance with GLP/GMP, biosafety, and ethical standards.
• Stay current with emerging trends in antibody engineering, ADC technology, and biomarker discovery.

Qualifications & Experience

Education: M.Sc. / M.Tech / Ph.D. in Molecular Biology, Biotechnology, Biochemistry, or related life science discipline.

Experience: 1–5 years of relevant experience in antibody or ADC research (academic or industry).

Skills:

• Strong hands‑on experience in molecular cloning, protein expression, purification, and assay development.
• Familiarity with analytical techniques (HPLC, LC‑MS) and cell‑based functional assays.
• Excellent data interpretation, communication, and teamwork skills.

What We Offer

• Opportunity to be part of a fast‑growing, innovation‑driven pharma organization
• Collaborative, research‑focused work culture
• Exposure to end‑to‑end drug development and cutting‑edge technologies
• Competitive compensation and growth opportunities.