Senior Scientist

Quraxia Pharmaceuticals

Haridwar

On-site

INR 900,000 - 1,300,000

Full time

46 hours ago
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Job summary

Quraxia Pharmaceuticals is seeking a Senior Chemist to design, develop, and characterize complex biomolecules including ADCs, peptides, proteins, and oligonucleotides. You will lead bioconjugation strategies, perform analytical characterization, and coordinate with cross-functional teams to advance discovery programs.

The role requires hands-on expertise in HPLC, LC-MS, UV-Vis, and protein/peptide chemistry, with a strong emphasis on data integrity, documentation, and collaboration within a

Qualifications

  • MSc/ MTech/ PhD in Chemistry, Biochemistry, Biotechnology, Chemical Biology or related field.
  • 3–8 years of experience in bioconjugation, peptide chemistry, protein chemistry, or nucleic acid chemistry (industry or advanced academic research).
  • Hands-on experience with analytical tools such as HPLC, LC-MS, UV-Vis spectroscopy, electrophoresis, and related platforms.
  • Strong understanding of biomolecule behavior, stability, purification, and characterization.
  • Excellent problem-solving, documentation, and communication skills.

Responsibilities

  • Contribute to the design and optimization of bioconjugation strategies for antibodies with chemical linkers and payloads.
  • Perform analytical characterization of ADCs, including assessment of conjugation efficiency, heterogeneity, and stability.
  • Support in vitro evaluation of ADC candidates through collaboration with cell biology and bioassay teams.
  • Document experimental findings, maintain batch records, and support development reports.
  • Assist in synthesis, modification, and purification of peptides and recombinant or engineered proteins.
  • Characterize peptides/proteins using biochemical and biophysical methods (HPLC, LC-MS, SDS-PAGE, UV-Vis).
  • Support formulation and stability studies to evaluate product behavior under various conditions.
  • Troubleshoot experimental challenges and propose improvements to workflows.
  • Support chemical modification or conjugation of oligonucleotides for therapeutic or diagnostic applications.
  • Perform purification and analytical characterization of oligonucleotides using appropriate chromatographic and spectrometric techniques.
  • Collaborate on structure–function evaluations, stability assessments, and impurity analysis.

Skills

Bioconjugation
Peptide chemistry
Protein chemistry
Nucleic acid chemistry
Analytical problem solving

Education

MSc/MTech/PhD in Chemistry/ Biochemistry/ Biotechnology/ Chemical Biology

Tools

HPLC
LC-MS
UV-Vis spectroscopy
SDS-PAGE

Job description

At Quraxia, we’re building a next-generation pharmaceutical R&D and innovation ecosystem — dedicated to discovering, developing, and delivering breakthrough therapies that improve patient outcomes. Our newly established state-of-the-art facility is designed to foster cutting-edge science, collaborative innovation, and ethical excellence in every project we undertake.

Role Overview

The Senior Chemist will play a key role in the design, development, and characterization of complex biomolecules including antibody-drug conjugates (ADCs), peptides, proteins, and oligonucleotides. The role requires strong expertise in bioconjugation chemistry, biomolecule analysis, and collaborative research workflows. The Senior Chemist will support discovery and development programs by executing experiments, generating high-quality data, and coordinating closely with cross-functional scientific teams.

Key Responsibilities
  • Contribute to the design and optimization of bioconjugation strategies for antibodies with chemical linkers and payloads.
  • Perform analytical characterization of ADCs, including assessment of conjugation efficiency, heterogeneity, and stability.
  • Support in vitro evaluation of ADC candidates through collaboration with cell biology and bioassay teams.
  • Document experimental findings, maintain batch records, and support development reports.
  • Assist in synthesis, modification, and purification of peptides and recombinant or engineered proteins.
  • Characterize peptides/proteins using biochemical and biophysical methods (HPLC, LC-MS, SDS-PAGE, UV-Vis).
  • Support formulation and stability studies to evaluate product behavior under various conditions.
  • Troubleshoot experimental challenges and propose improvements to workflows.
  • Support chemical modification or conjugation of oligonucleotides for therapeutic or diagnostic applications.
  • Perform purification and analytical characterization of oligonucleotides using appropriate chromatographic and spectrometric techniques.
  • Collaborate on structure–function evaluations, stability assessments, and impurity analysis.
Documentation & Compliance
  • Maintain accurate experimental records, reports, and inventory logs according to GLP/GMP standards.
  • Follow all safety, biosafety, and quality guidelines within the laboratory.
  • Support regulatory documentation efforts by providing analytical data and experimental summaries.
Qualifications & Experience
  • M.Sc. / M.Tech / Ph.D. in Chemistry, Biochemistry, Biotechnology, Chemical Biology, or related field.
  • 3–8 years of experience in bioconjugation, peptide chemistry, protein chemistry, or nucleic acid chemistry (industry or advanced academic research).
  • Hands-on experience with analytical tools such as HPLC, LC-MS, UV-Vis spectroscopy, electrophoresis, and related platforms.
  • Strong understanding of biomolecule behavior, stability, purification, and characterization.
  • Excellent problem-solving, documentation, and communication skills.
What We Offer
  • Opportunity to be part of a fast-growing, innovation-driven pharma organization
  • Collaborative, research-focused work culture
  • Exposure to end-to-end drug development and cutting-edge technologies
  • Competitive compensation and growth opportunities.
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