Bioinformatics / Computational Genomics Expert

Encore IT Solutions Inc; India; Remote; INR 1,674,000 - 3,348,000; Full time

Job summary

Encore IT Solutions Inc seeks a Bioinformatics / Computational Genomics Expert for a 4-week remote engagement in India. Ph.D. is mandatory. The role focuses on designing challenging genomics tasks and reference solutions to test AI agents in a Python-based environment.

You will craft realistic datasets (FASTA/FASTQ/VCF/BAM) and build reproducible workflows, leveraging Biopython, PLINK, and standard genomics tools. Strong Python and Linux skills are essential.

Qualifications

• Ph.D., postdoctoral experience, or equivalent research experience in Bioinformatics, Computational Biology, Genomics, Computational Genetics, or a closely related discipline.
• Strong hands-on programming experience in Python.
• Experience analyzing biological sequence or genomics datasets.
• Comfortable working in Linux/command-line computational environments.

Responsibilities

• Design novel, model-challenging tasks in computational genomics and bioinformatics.
• Develop tasks requiring multi-step analyses using Python and command-line tools.
• Create clear task specifications, inputs, outputs, and ground truths.
• Develop reproducible reference solutions and workflows in the Python stack.
• Ensure tasks are scientifically correct and solvable from supplied data.
• Document deliverables for reproducibility and client use.

Skills

Python programming

Linux/CLI

Biology data analysis

Education

Ph.D. or equivalent research experience

Tools

Biopython

Pandas

NumPy

SciPy

samtools

bcftools

BLAST

PLINK

Job description

Job Designation: Bioinformatics / Computational Genomics Expert

Experience:1-10 Years (Ph.D is Mandatory)

Work Mode: Remote

Contract Duration: 4 Weeks

Role Overview

We are seeking Bioinformatics and Computational Genomics experts to design challenging, agentic genomics tasks and reference solutions for GeneBench Pro. You will create realistic computational biology problems that require an AI agent to interpret biological data, write and execute code, work across scientific files, and produce objectively verifiable outputs.

Tasks should reflect authentic genomics and bioinformatics workflows rather than standalone biology questions.

Environment

Each GeneBench Pro problem is a self-contained scientific analysis. Agents receive an isolated workspace with a short prompt, data files, and a standard bioinformatics stack including Python, scientific computing libraries, and basic genomics packages such as PLINK 2.0. Reference solutions must run in this Python-based environment.

Key Responsibilities

• Design novel, model-challenging tasks in computational genomics and bioinformatics.
• Design tasks that test higher-order scientific judgment, including handling ambiguous or messy data, identifying artifacts, selecting appropriate analytical approaches, revising assumptions based on intermediate results, and determining when conclusions are decision-ready.
• Build tasks involving realistic scientific data such as FASTA/FASTQ, VCF, BAM/SAM, BED, TSV/CSV, sequence annotations, expression data, germline or somatic variant data, or other genomics artifacts.
• Develop tasks requiring multi-step analysis using Python, command-line tools, or established bioinformatics libraries.
• Create clear task specifications, input datasets, expected output schemas, and deterministic or objectively verifiable ground truths.
• Develop expert reference solutions and reproducible computational workflows that run in the provided Python stack.
• Validate that tasks are scientifically correct, solvable from the supplied information, and sufficiently challenging for frontier AI models.
• Design robust grading criteria that distinguish scientifically correct solutions from superficially plausible outputs.
• Ensure all deliverables are well documented, reproducible, and client-ready.
• Maintain high quality and throughput while incorporating reviewer feedback.
• Communicate progress, blockers, and scientific or technical requirements to project leads and reviewers.

Qualifications Required

• Ph.D., postdoctoral experience, or equivalent research experience in Bioinformatics, Computational Biology, Genomics, Computational Genetics, or a closely related discipline.
• Strong hands-on programming experience in Python.
• Experience analyzing biological sequence or genomics datasets.
• Comfortable working in Linux/command-line computational environments.

Preferred

• Experience with genomics workflows such as variant analysis, tran omics, sequence analysis, phylogenetics, population genetics, functional genomics, or clinical genomics.
• Familiarity with common bioinformatics libraries and tools such as Biopython, pandas, NumPy, SciPy, samtools, bcftools, BLAST, PLINK, or equivalent tools.
• Experience developing reproducible scientific pipelines.
• Experience evaluating AI/LLM systems on computational scientific tasks.
• Strong understanding of experimental and biological context behind computational analyses.

Bonus Points For

• Experience with AI agents or coding agents.
• Experience designing benchmark datasets or automated graders.
• Publications involving computational genomics or bioinformatics.
• Experience with Docker/containerized scientific workflows.