Associate Director, PKPD / Pharmacometrics / NONMEM / SAS Programmer

AstraZeneca; Bengaluru; On-site; INR 2,000,000 - 3,500,000; Full time

Job summary

AstraZeneca is seeking an Associate Director, PKPD / Pharmacometrics / NONMEM / SAS Programmer in Bengaluru, India. This role involves leading data programming efforts, contributing to regulatory submissions, and applying advanced data integration techniques for drug development.

The ideal candidate will have over 10 years of SAS programming experience, a strong understanding of pharmacokinetics, and excellent communication skills. We promote a vibrant work culture with a blend of remote and on-site responsibilities.

Qualifications

• 10+ years of SAS programming experience.
• Strong understanding of pharmacokinetics and pharmacodynamics.
• Experience in drug development (early and late-stage).
• Proficient English communication skills.

Responsibilities

• Program, validate, and diagnose data to support analyses.
• Integrate data for Pharmacometrics Modeling and Simulation.
• Contribute to regulatory documents and compliance initiatives.
• Lead interdisciplinary team efforts.

Skills

SAS programming

Pharmacokinetics

Data preparation practices

Problem-solving skills

Excellent communication skills

Education

Bachelor's degree in relevant field

MS preferred

Tools

NONMEM

SAS/R

Python

Job description

Associate Director, PKPD / Pharmacometrics / NONMEM / SAS Programmer

Introduction

Are you interested in shaping the future of drug development? We are looking for an Associate Director, PKPD / Pharmacometrics / NONMEM / SAS Programmer to join our Clinical Pharmacology and Quantitative Pharmacology Data Programming team. In this position you will prepare, program, validate, and diagnose data to support Pharmacometrics and Clinical Pharmacology analyses and influence critical decision making throughout all phases of drug development and regulatory interactions.

Accountabilities & Responsibilities

• Expert data cleaning, manipulation, transformation, and integration at both the study and compound level.
• Apply advanced data integration techniques to pool data from study and compound‑level SDTM/ADaM datasets and prepare analysis‑ready data for Pharmacometrics Modeling and Simulation (M&S) software, such as NONMEM.
• Support study design, dose selection, dose justification, and go/no‑go decisions.
• Contribute to regulatory documents and internal initiatives that advance the Pharmacometrics discipline and ensure compliance with Good Clinical Practice (GCP) regulations.
• Lead interdisciplinary team efforts and support regulatory submissions.

Essential Skills & Experience

• 10+ years of hands‑on SAS programming experience in preparing pooled data sets across studies.
• Strong understanding of pharmacokinetics, pharmacodynamics, and their application in drug development.
• Advanced SAS/R programming skills.
• Expert knowledge of data preparation and programming practices (CDISC, SDTM, ADaM).
• Demonstrated data programming and clinical development expertise.
• Knowledge of global regulatory, compliance, processes, and standards.
• Capability to develop tools to support data integration and visualization.
• Bachelor's degree; MS preferred with relevant experience required.
• Experience in early and late‑stage drug development.
• Excellent problem‑solving, communication, and project management skills.
• Proficient oral and written English communication skills.
• Knowledge in pharmacology, drug targets, and core therapeutic areas (e.g., Oncology, Respiratory, Renal, Metabolism).
• Quantitative/Scientific background (Statistics, Engineering, Biological Science).

Desirable Skills & Experience

• Expertise in data preparation and programming to support Pharmacometrics M&S software (e.g., NONMEM, Monolix, R, Matlab).
• Scientific publishing in the field of pharmacometrics.
• Experience with Python programming.

Benefits & Work Environment

We encourage in‑person work, requiring a minimum of three days per week in the office, while maintaining flexibility to balance remote and on‑site work. Join our dynamic environment that values creativity, bold decision‑making, and global collaboration to advance healthcare breakthroughs.

Equal Opportunity Statement

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with a wide range of perspectives, and harnessing industry‑leading skills. We comply with all applicable laws and regulations on non‑discrimination in employment and work authorization, and we encourage qualified applicants from all backgrounds to apply.

Closing Information

Date Posted: 16‑Sept‑2025
Closing Date: 30‑Sept‑2025