Senior Process Engineering Leader – API Manufacturing

AstraZeneca; Dublin; On-site; EUR 90,000 - 150,000; Full time

Job summary

AstraZeneca in Dublin is seeking an Associate Director Process Engineering to lead API Commercialisation within APICOM. The role focuses on applying deep chemical engineering expertise to scale up and transfer processes for late-stage clinical and commercial API, ensuring safe, compliant operations from design through validation.

As a senior SME, you will mentor colleagues, perform risk assessments, audits, and collaborate across chemistry, manufacturing, and quality teams while integrating GMP

Qualifications

• Degree and/or PhD in Chemical Engineering.
• Chartered Chemical Engineer credential.
• Experience in pharmaceutical/fine chemical manufacturing.
• Understanding of unit operations such as mixing, distillation, liquid-liquid extraction, isolation and drying.

Responsibilities

• Carry out process engineering for new API projects in a state-of-the-art facility including scale-up assessments and safety reviews.
• Utilise engineering calculations to optimise equipment performance and ensure compliance with standards.
• Act as SME during internal and external audits and provide guidance on process-related matters.
• Lead or participate in risk assessments (HAZOPs/HAZIDs) and ensure GMP and SHE integration in project plans.
• Oversee large-scale capital projects and collaborate with cross-functional teams to implement new technologies.
• Mentor and supervise junior colleagues and university students.

Skills

Process safety

GMP knowledge

Communication

Leadership

Mentoring

Education

Degree in Chemical Engineering

Chartered Chemical Engineer

Tools

Aspen Plus

DynoChem

gPROMS

CFD

Job description

AstraZeneca in Dublin is seeking an Associate Director Process Engineering to lead API Commercialisation within APICOM. The role focuses on applying deep chemical engineering expertise to scale up and transfer processes for late-stage clinical and commercial API, ensuring safe, compliant operations from design through validation.

As a senior SME, you will mentor colleagues, perform risk assessments, audits, and collaborate across chemistry, manufacturing, and quality teams while integrating GMP