Senior PK/PD Modeling Programmer (NONMEM)

Cytel; Ireland; Remote; EUR 90,000 - 120,000; Full time

Job summary

Cytel is seeking a Senior Statistical Programmer to be sponsor-dedicated and embedded with a pharmaceutical client in Ireland. You will support PK/PD modeling, data analysis, submission-ready deliverables and data flow guidance across functions.

The role requires strong SAS programming experience in clinical trials, CDISC SDTM/ADaM, and leadership in study-level data handling. Collaboration across global teams is essential, with a focus on high-quality, timely outputs.

Qualifications

• Bachelor's degree in Statistics, Computer Science, Mathematics or related field.
• Minimum 6 years of SAS programming with clinical trial data in pharma/biotech; 4+ years with Master’s degree.
• Study lead experience preferred; reporting and analysis leadership is a plus.
• Strong SAS data manipulation, analysis and reporting skills.
• Solid experience implementing CDISC SDTM/ADaM standards.
• Issues QC/validation and quality-driven output for submissions.
• Experience supporting immunology, respiratory or oncology studies a plus.

Responsibilities

• Prepare programming scripts (SAS/R) for NONMEM input datasets for PK/PD analyses.
• QC NONMEM datasets and document QC findings with actions.
• Generate e-submission packages including define.xml and related files.
• Provide DataFlow process guidance for CPP team and cross-department coordination.
• Interact with Data Management, Programming, BAN/BDS, EPOD and external vendors.
• Revise SOPs, templates, and training materials for CPP processes.
• Improve dataset creation, QC workflows and e-submission packaging scripts.

Skills

SAS programming

Clinical trial data handling

CDISC SDTM/ADaM

Data manipulation

Efficacy analysis

QC/validation

Submissions experience

Education

Bachelor's degree in Statistics/Math/CS

Master's degree preferred

Tools

SAS

R

Job description

Cytel is seeking a Senior Statistical Programmer to be sponsor-dedicated and embedded with a pharmaceutical client in Ireland. You will support PK/PD modeling, data analysis, submission-ready deliverables and data flow guidance across functions.

The role requires strong SAS programming experience in clinical trials, CDISC SDTM/ADaM, and leadership in study-level data handling. Collaboration across global teams is essential, with a focus on high-quality, timely outputs.