Associate Director, Clinical Pharmacology

Grifols Shared Services North America, Inc; Dublin; On-site; EUR 120,000 - 180,000; Full time

Benefits offered by this job

Competitive salary package

Group pension scheme

Private medical insurance

Career development opportunities

Internal promotion focus

Education and professional development

Wellness and social initiatives

Mostly remote working

Job summary

Grifols is seeking an Associate Director, Clinical Pharmacology in Ireland to lead non‑clinical and early clinical pharmacology strategy across drug development programs. You will provide PK/PD expertise, modeling & simulation, and Model‑Informed Drug Development to support dose selection, study design, and regulatory submissions.

You will partner cross‑functionally with clinicians and statisticians, mentor junior scientists, and ensure scientific excellence and regulatory compliance while

Qualifications

• Doctoral-level training in clinical pharmacology or related discipline.
• Experience supporting pharmacology activities across non‑clinical and early clinical development.
• Ability to apply scientific rigor in a fast-paced, collaborative setting.

Responsibilities

• Lead PK/PD data analysis and modeling across programs.
• Apply quantitative methods to support non‑clinical and early clinical programs.
• Contribute to regulatory interactions and submissions (INDs, BLA, MAAs, etc.).
• Communicate complex concepts to cross‑functional teams and external stakeholders.
• Provide scientific leadership in matrixed teams and drive strategy.
• Oversee study-level pharmacology activities including protocol and SAP.
• Design and implement pharmacology plans and ensure best practices.
• Partner with clinicians and statisticians to optimise dosing and study design.

Skills

Clinical pharmacology

PK/PD

Data analysis

Regulatory knowledge

Education

PhD or PharmD or post‑doctoral in related field

Tools

Phoenix WinNonlin

NONMEM

Job description

Would you like to join an international team working to improve the future of healthcare? Do you want to enhance the lives of millions of people? Grifols is a global healthcare company that since 1909 has been working to improve the health and well‑being of people around the world. We are leaders in plasma‑derived medicines and transfusion medicine and develop, produce and market innovative medicines, solutions and services in more than 110 countries and regions.

At Grifols, we believe that diversity adds value to our business, our teams, and our culture. We are committed to equal employment opportunities that foster an inclusive environment.

POSITION SUMMARY:

The Associate Director, Clinical Pharmacology will responsible for leading non‑clinical and early clinical pharmacology strategy across drug development programs. Provides expertise in PK/PD, modeling & simulation, and Model‑Informed Drug Development (MIDD) to support dose selection, study design, and regulatory submissions. Partners cross‑functionally with clinicians and statisticians, represents Pharmacology on global teams, and mentors junior scientists while ensuring scientific excellence and regulatory compliance.

What You Will Do

• Lead PK/PD data analysis and modeling activities, applying mechanistic and population modeling approaches using tools such as Phoenix WinNonlin, NONMEM, and related platforms.
• Apply quantitative and statistical methods to support non‑clinical and early‑phase clinical pharmacology programs.
• Contribute to regulatory interactions and submissions, including INDs, BLAs, MAAs, Investigator's Brochures, briefing packages, and responses to agency queries.
• Communicate complex clinical pharmacology concepts clearly and effectively to cross‑functional and external stakeholders.
• Provide scientific leadership in matrixed teams, driving pharmacology strategy, problem‑solving, and decision‑making across programs.
• Lead the analysis, integration, and reporting of clinical pharmacology data to inform dose selection and study design.
• Design and implement pharmacology plans and ensure best practices across project teams.
• Partner with clinicians and statisticians to optimise dosing strategies and clinical study designs.
• Oversee study‑level pharmacology activities, including protocol and SAP development, execution, and reporting.
• Drive the design and execution of Model‑Informed Drug Development (MIDD) strategies.
• Represent Pharmacology on global program teams, clinical sub teams, and other multifunctional groups.
• Mentor and coach junior colleagues and team members.
• Stay current with scientific literature, regulatory guidelines, and internal SOPs.

What You'll Bring

• A doctoral degree (PhD) or equivalent professional training (PharmD), or post‑doctoral experience in clinical pharmacology, pharmacokinetics, pharmacology, toxicology, pharmaceutics, or a related scientific discipline.
• A minimum of 3+ years of relevant industry or academic experience supporting pharmacokinetic, pharmacodynamic, and broader pharmacology activities across non‑clinical and early clinical drug development programs.
• Hands‑on experience contributing to pharmacology strategy and execution within pharmaceutical or biotechnology environments, with the ability to apply scientific rigor in a fast‑paced, collaborative setting.

Our Benefits Include

• A highly competitive salary package
• Group pension scheme - Contribution rates are (3%/ 5%/ 7%) and company will match
• Private medical insurance for the employee
• Ongoing career development opportunities within a rapidly growing organisation
• Strong focus on succession planning and internal promotion
• Dedicated education and professional development allowance
• Wellness and social initiatives, including activities such as padel and summer events
• Mostly remote working model, supporting work-life balance

We understand that self‑doubt can hold talented individuals back from applying for opportunities. We encourage everyone who meets the qualifications to apply - we're excited to hear from you

Location:

Grange Castle International Business Park, Grange, Co. Dublin, D22 K2R3 ( more about Grifols

Type:

Regular Full-Time

Job Category:

Clinical Trials