Translational Immunology Postdoc: Treg & IBD Research

King's College London; Greater London; On-site; GBP 38,000 - 46,000; Full time

Job summary

King’s College London invites applications for a Postdoctoral Research Associate to contribute to an innovative translational immunology programme. The role focuses on regulatory T cells in IBD lesions, collaborating with gastroenterologists and immunologists at Guy's and St Thomas' NHS Foundation Trust and KCL.

You will validate scRNA-seq and spatial transcriptomic findings, helping to define therapeutic targets while building an independent research profile in a multidisciplinary setting.

Qualifications

• PhD in Immunology, Systems Biology, or a related discipline.
• Experience in knockout generation using CRISPR.
• Experience in cellular and molecular immunology techniques including flow cytometry, Treg expansion, intracellular cytokine assays, and functional immune assays.

Responsibilities

• Investigate regulatory T cell biology to identify suppressive Treg subsets in IBD gut lesions.
• Provide lab-based functional validation of scRNA-seq and spatial transcriptomic findings.
• Translate findings into clinically relevant therapeutic targets in a translational immunology programme.

Skills

Flow cytometry

CRISPR knockout

Spatial data analysis

Python

R

Education

PhD in Immunology

PhD in Systems Biology

Tools

Imaging Mass Cytometry (IMC)

Job description

King’s College London invites applications for a Postdoctoral Research Associate to contribute to an innovative translational immunology programme. The role focuses on regulatory T cells in IBD lesions, collaborating with gastroenterologists and immunologists at Guy's and St Thomas' NHS Foundation Trust and KCL.

You will validate scRNA-seq and spatial transcriptomic findings, helping to define therapeutic targets while building an independent research profile in a multidisciplinary setting.